SCHEMBL19206601

SCHEMBL19206601

NCC(O)c1cc[c]cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.58
NFKB1 P19838 3/20 0.58
TSHR P16473 2/20 0.58
HIF1A Q16665 2/20 0.58
HTR3A P46098 1/20 0.58
TDP1 Q9NUW8 4/20 0.56
KDM4E B2RXH2 4/20 0.56
APEX1 P27695 3/20 0.56
ALOX15 P16050 1/20 0.56
BLM P54132 5/20 0.47
MAPT P10636 3/20 0.47
RECQL P46063 3/20 0.47
ADRB2 P07550 3/20 0.47
ADRA2A P08913 3/20 0.47
ADRA2B P18089 3/20 0.47
ADRA2C P18825 3/20 0.47
HPGD P15428 2/20 0.47
ADRB1 P08588 2/20 0.47
ADRA1D P25100 2/20 0.47
LMNA P02545 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21750404 0.82 TAAR1 (0.39) TAAR1NFKB1TSHRHIF1AHTR3A
SCHEMBL4074768 0.82 TAAR1 (0.80) TAAR1NFKB1TSHRHIF1AHTR3A
SCHEMBL28364 0.78 TSHR (0.37) TAAR1NFKB1TSHRHIF1AHTR3A
SCHEMBL22363024 0.76 LMNA (0.33) TAAR1NFKB1TSHRHIF1AHTR3A
SCHEMBL19468908 0.76 LMNA (0.38) TAAR1NFKB1TSHRHIF1AHTR3A
SCHEMBL317586 0.76 LMNA (0.60) TAAR1NFKB1TSHRHIF1AHTR3A
SCHEMBL2021 0.75 TAAR1 (0.62) TAAR1NFKB1TSHRHIF1AHTR3A
SCHEMBL175554 0.75 TAAR1 (0.62) TAAR1NFKB1TSHRHIF1AHTR3A
SCHEMBL147501 0.75 TAAR1 (0.62) TAAR1NFKB1TSHRHIF1AHTR3A
SCHEMBL6274882 0.74 RIPK1 (0.35) TAAR1NFKB1TSHRHIF1AHTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210220241-A1 Body Sculpting SCULPT B.V. (NL) 2021-07-22 US disclosed
US-20170231885-A1 Body Sculpting SCULPT B.V. (NL) 2017-08-17 US disclosed
CN-106999465-A body shaping 斯科勒普特有限公司 2017-08-01 CN disclosed