SCHEMBL1921483

SCHEMBL1921483

CCCCn1c2ccc(Cl)cc2c2cc(Cl)ccc21

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 7/20 0.67
PSEN2 P49810 7/20 0.67
APH1B Q8WW43 7/20 0.67
NCSTN Q92542 7/20 0.67
APH1A Q96BI3 7/20 0.67
PSENEN Q9NZ42 7/20 0.67
RORA P35398 4/20 0.54
RORC P51449 4/20 0.54
RORB Q92753 4/20 0.54
NR1H2 P55055 1/20 0.54
PTGER4 P35408 1/20 0.51
PGR P06401 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1923371 0.92 PSEN1 (0.63) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL551120 0.90 PSEN1 (0.77) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL1921824 0.89 PSEN1 (0.57) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL29543602 0.83 RORA (0.55) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL8086740 0.83 RORA (0.55) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL13899693 0.81 PSEN1 (0.66) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL1921889 0.81 ALDH1A1 (0.60) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL1921261 0.80 PTGER4 (0.72) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL31609293 0.80 PSEN1 (0.54) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL8831402 0.80 PSEN1 (0.54) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 US disclosed