SCHEMBL19218247

SCHEMBL19218247

c1ccc(N(c2ccc3c(c2)C2(c4ccccc4-c4ccccc42)c2ccccc2-3)c2ccc3c4ccccc4c4ccccc4c3c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.39
KDM4E B2RXH2 2/20 0.34
MAPT P10636 2/20 0.34
ALDH1A1 P00352 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
LMNA P02545 1/20 0.31
OPRK1 P41145 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CRHBP P24387 1/20 0.30
ATM Q13315 1/20 0.30
CRHR2 Q13324 1/20 0.30
TLR9 Q9NR96 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19218356 0.95 PDK2 (0.38) PDK2KDM4EMAPTMEN1KMT2A
SCHEMBL19218234 0.95 PDK2 (0.38) PDK2KDM4EMAPTMEN1KMT2A
SCHEMBL21559419 0.93 MEN1 (0.36) PDK2KDM4EMAPTALDH1A1L3MBTL1
SCHEMBL21559421 0.93 PDK2 (0.38) PDK2KDM4EMAPTALDH1A1L3MBTL1
SCHEMBL19218218 0.93 PDK2 (0.38) PDK2MAPTL3MBTL1MEN1KMT2A
SCHEMBL19218222 0.93 PDK2 (0.38) PDK2MAPTL3MBTL1MEN1KMT2A
SCHEMBL20707548 0.93 KDM4E (0.38) PDK2KDM4EMAPTALDH1A1L3MBTL1
SCHEMBL20172977 0.93 PDK2 (0.38) PDK2KDM4EMAPTALDH1A1L3MBTL1
SCHEMBL20218306 0.92 PDK2 (0.40) PDK2
SCHEMBL20218265 0.92 PDK2 (0.37) PDK2KDM4EMAPTALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230024114-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2023-01-26 US disclosed
US-20220376178-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2022-11-24 US disclosed
US-11380853-B2 Organic light emitting diode and organic light emitting device including the same LG DISPLAY CO., LTD. (KR) 2022-07-05 US disclosed
US-11069858-B2 Amine-based compound and organic light emitting device comprising same LG CHEM, LTD. (KR) 2021-07-20 US disclosed
US-10991886-B2 Amine-based compound and organic light emitting device comprising same LG CHEM, LTD. 2021-04-27 US disclosed
EP-3330249-B1 AMINE-BASED COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2021-01-06 EP disclosed
US-20200212312-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2020-07-02 US disclosed
US-20190198763-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2019-06-27 US disclosed
US-20190148650-A1 Organic Light Emitting Device LG CHEM, LTD. (KR) 2019-05-16 US disclosed
US-10243148-B2 Aromatic amine compound, and organic electroluminescent elements including the compound IDEMITSU KOSAN CO., LTD. (JP) 2019-03-26 US disclosed
EP-3439062-A1 ORGANIC LIGHT EMITTING ELEMENT LG Chem, Ltd. (KR) 2019-02-06 EP disclosed
EP-3330249-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2018-06-06 EP disclosed
US-20170229649-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-08-10 US disclosed
US-20170229649-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2017-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190198763-A1 AMINE-BASED COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME CYP1A1, CYP1B1, CRY1 PDK2 2479/4885KDM4E 1007/4885MAPT 534/4885
US-10991886-B2 Amine-based compound and organic light emitting device comprising same TYR, PNMT, AOC2 PDK2 2736/4885KDM4E 489/4885MAPT 60/4885
US-10243148-B2 Aromatic amine compound, and organic electroluminescent elements including the compound H1-10, H1-0, H1-4 PDK2 2391/4885KDM4E 942/4885MAPT 699/4885
US-20170229649-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE L1CAM, LEF1, PIEZO1 PDK2 2204/4885KDM4E 2978/4885MAPT 1677/4885
US-20200212312-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME TYR, ALDH1A2, CYBA PDK2 785/4885KDM4E 3058/4885MAPT 852/4885
US-11069858-B2 Amine-based compound and organic light emitting device comprising same CYP1A1, CYP1B1, CRY1 PDK2 2479/4885KDM4E 1007/4885MAPT 534/4885
US-11380853-B2 Organic light emitting diode and organic light emitting device including the same TYR, ALDH1A2, CYBA PDK2 785/4885KDM4E 3058/4885MAPT 852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.