Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2984350 | 0.98 | ALDH1A1 (0.41) | ALDH1A1TSHRMAOAMAOBS1PR2 | |
| SCHEMBL22541110 | 0.94 | CA14 (0.39) | ALDH1A1TSHRMAOAMAOBHDAC1 | |
| SCHEMBL13355834 | 0.87 | FPR3 (0.38) | HDAC1HDAC2HDAC6CA14PAOX | |
| SCHEMBL26900686 | 0.87 | CA14 (0.41) | MAOAMAOBHDAC1HDAC2HDAC6 | |
| SCHEMBL16982892 | 0.85 | EPHX2 (0.42) | MAOAMAOBHDAC1HDAC2HDAC6 | |
| SCHEMBL15223854 | 0.84 | PAOX (0.46) | ALDH1A1MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL22771101 | 0.84 | CA14 (0.42) | MAOAMAOBHDAC1HDAC2HDAC6 | |
| SCHEMBL30999444 | 0.84 | TDP1 (0.42) | ALDH1A1MAOAMAOBHDAC1HDAC2 | |
| SCHEMBL22113731 | 0.84 | HDAC1 (0.41) | ALDH1A1TSHRMAOAMAOBHDAC1 | |
| SCHEMBL25352467 | 0.84 | CA14 (0.48) | ALDH1A1MAOAMAOBHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11802114-B2 | Compounds and methods for detection of superoxide | PROMEGA CORPORATION (US) | 2023-10-31 | — | — | US | disclosed |
| US-20170224829-A1 | Prodrugs Comprising an Aminoalkyl Glycine Linker | ASCENDIS PHARMA A/S (DK) | 2017-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170224829-A1 | Prodrugs Comprising an Aminoalkyl Glycine Linker | DNPEP, PAM, ASNS | ALDH1A1 725/4885TSHR 2899/4885MAOA 1637/4885 |
| US-11802114-B2 | Compounds and methods for detection of superoxide | SOD1, GPX4, SOD3 | ALDH1A1 198/4885TSHR 4831/4885MAOA 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.