Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230647 | 0.83 | RAB9A (0.43) | RAB9AMEN1KMT2AMAPTCA12 | |
| SCHEMBL19230805 | 0.81 | ESR1 (0.49) | RAB9AMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL19230310 | 0.81 | ESR1 (0.49) | RAB9AMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL19230656 | 0.81 | ESR1 (0.49) | RAB9AMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL19230672 | 0.81 | ESR2 (0.46) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL19230649 | 0.79 | NPC1 (0.37) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23800712 | 0.73 | NPC1 (0.48) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16372412 | 0.71 | MTNR1A (0.46) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19230591 | 0.70 | DRD2 (0.43) | SMN1; SMN2TSHRKDM4ECA12CA1 | |
| SCHEMBL18397240 | 0.70 | CSF1R (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602811-B | FXR receptor agonists | 轩竹生物科技有限公司 | 2021-11-16 | — | — | CN | disclosed |
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |