Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | IDE | P14735 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19240002 | 0.80 | MEN1 (0.42) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL19240024 | 0.77 | GLO1 (0.41) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL19240082 | 0.74 | MEN1 (0.38) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL19239990 | 0.74 | MEN1 (0.40) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL19240046 | 0.73 | CES2 (0.40) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL19240005 | 0.71 | THRB (0.38) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL19239993 | 0.69 | MEN1 (0.34) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL19240023 | 0.67 | ALDH1A1 (0.43) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL19038917 | 0.66 | MAPT (0.55) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL14015985 | 0.63 | MEN1 (0.36) | KMT2AMEN1MAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170235032-A1 | OPTICAL FILM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-17 | — | — | US | disclosed |
| US-20170235032-A1 | OPTICAL FILM | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-17 | — | — | US | disclosed |
| US-20150307465-A1 | Iminothiadiazine Dioxide Compounds as BACE Inhibitors, Compositions and Their Use | MERCK SHARP & DOHME CORP. (US) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307465-A1 | Iminothiadiazine Dioxide Compounds as BACE Inhibitors, Compositions and Their Use | BACE1, BACE2, APP | KMT2A 3201/4885MEN1 977/4885MAPT 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.