Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29602493 | 1.00 | PIM1 (0.47) | PIM1CYP2A6MAOBMAOACES2 | |
| SCHEMBL4355959 | 0.84 | SMN1; SMN2 (0.53) | PIM1MAOBMAOACES2CES1 | |
| SCHEMBL1926473 | 0.83 | HDAC1 (0.63) | CYP2A6CES2CES1HDAC1HDAC6 | |
| SCHEMBL30881474 | 0.83 | HDAC1 (0.63) | CYP2A6CES2CES1HDAC1HDAC6 | |
| SCHEMBL385343 | 0.83 | LMNA (0.53) | PIM1MAOBMAOACES2CES1 | |
| SCHEMBL75801 | 0.82 | CES2 (0.67) | CYP2A6MAOBMAOACES2CES1 | |
| SCHEMBL29669896 | 0.82 | CES2 (0.67) | CYP2A6MAOBMAOACES2CES1 | |
| SCHEMBL16952769 | 0.82 | PIM1 (0.42) | PIM1MAOBMAOACES2CES1 | |
| SCHEMBL4113200 | 0.81 | MAPT (0.61) | MAPTRAB9ANPC1LMNA | |
| Hydrochloric Acid SCHEMBL1478519 | 0.81 | LMNA (0.52) | PIM1MAOBMAOACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119019281-A | Preparation method of 4-acetyl-2-methylbenzonitrile | 黑龙江立科新材料有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-116041212-A | Preparation and application of difluoro olefin ether and oxime ether derivatives | 安徽农业大学 | 2023-05-02 | — | — | CN | claimed |
| CN-116041212-B | Preparation and application of difluoro olefin oxime ether derivative | 安徽农业大学 | 2025-06-13 | — | — | CN | disclosed |
| US-20250091998-A1 | A PROCESS FOR THE PREPARATION OF CARBAMOYL BENZAMIDE PHENYL ISOXAZOLINE CLASS DRUG/S AND ITS INTERMEDIATES | ZENFOLD SUSTAINABLE TECHNOLOGIES PRIVATE LIMITED (IN) | 2025-03-20 | — | — | US | disclosed |
| CN-119019281-A | Preparation method of 4-acetyl-2-methylbenzonitrile | 黑龙江立科新材料有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-119019281-A | Preparation method of 4-acetyl-2-methylbenzonitrile | 黑龙江立科新材料有限公司 | 2024-11-26 | — | — | CN | disclosed |
| EP-3227270-B1 | HETEROCYCLIC DERIVATIVES AND USE THEREOF | C&C RES LAB (KR) | 2024-11-13 | — | — | EP | disclosed |
| CN-118324614-A | Synthesis method of 2-methyl-4-formaldoxime benzoic acid or derivative thereof | 珠海保税区丽珠合成制药有限公司 | 2024-07-12 | — | — | CN | disclosed |
| WO-2024006974-A2 | ANTIMALARIAL COMPOUNDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-01-04 | — | — | WO | disclosed |
| WO-2024006971-A2 | ANTIMALARIAL COMPOUNDS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-01-04 | — | — | WO | disclosed |
| EP-4227307-A1 | PYRAZOLOPYRAZINE COMPOUNDS AS SHP2 INHIBITORS | Genzyme Corporation (US) | 2023-08-16 | — | — | EP | disclosed |
| US-20040220194-A1 | 2-Alkynyl-and 2-alkenyl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists | SCHERING CORPORATION | 2004-11-04 | — | — | US | disclosed |
| EP-1431293-A1 | WATER-SOLUBLE PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | Kowa Co., Ltd. (JP) | 2004-06-23 | — | — | EP | disclosed |
| US-20040002497-A1 | Water-soluble phenylpyridazine compounds and compositions containing the same | KOWA CO., LTD. (JP) | 2004-01-01 | — | — | US | disclosed |
| US-20030119838-A1 | Water-soluble phenylpyridazine compounds and compositions containing the same | KOWA CO., LTD. (JP) | 2003-06-26 | — | — | US | disclosed |
| EP-0191496-B1 | TRIAZINE DERIVATIVES, A PROCESS FOR PREPARING THE DERIVATIVES, AND HERBICIDES CONTAINING THE DERIVATIVES AS THE EFFECTIVE COMPONENT | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-10-31 | — | — | EP | disclosed |
| CN-1004204-B | Herbicide containing triazine derivative as active ingredient | 出光兴产株式会社 | 1989-05-17 | — | — | CN | disclosed |
| US-4680054-A | Triazine derivatives, a process for preparing the derivatives, and herbicides containing the derivatives as the effective component | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1987-07-14 | — | — | US | disclosed |
| EP-0191496-A2 | Triazine Derivatives, a process for preparing the derivatives, and herbicides containing the derivatives as the effective component | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1986-08-20 | — | — | EP | disclosed |
| CN-86100884-A | Process for preparing triazine derivatives and herbicides containing the derivatives as active ingredient | — | 1986-08-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119838-A1 | Water-soluble phenylpyridazine compounds and compositions containing the same | IL1A, IL1B, IL1R1 | PIM1 338/4885CYP2A6 589/4885MAOB 2633/4885 |
| US-20040002497-A1 | Water-soluble phenylpyridazine compounds and compositions containing the same | IL1A, IL1B, IL1R1 | PIM1 326/4885CYP2A6 530/4885MAOB 2527/4885 |
| US-20040220194-A1 | 2-Alkynyl-and 2-alkenyl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists | ADORA2A, ADORA3, ADORA1 | PIM1 4258/4885CYP2A6 1757/4885MAOB 313/4885 |
| US-20250091998-A1 | A PROCESS FOR THE PREPARATION OF CARBAMOYL BENZAMIDE PHENYL ISOXAZOLINE CLASS DRUG/S AND ITS INTERMEDIATES | CYP3A7, CYP1A2, CYP1B1 | PIM1 1869/4885CYP2A6 56/4885MAOB 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.