SCHEMBL1924635

SCHEMBL1924635

CC(C)(CNS(=O)(=O)c1cc2ccccc2o1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 13/20 0.46
CA2 P00918 1/20 0.46
MMP13 P45452 1/20 0.45
BCAT1 P54687 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1926052 0.80 MMP2 (0.56) CCR2CA2BCAT1KMT2A
SCHEMBL4846244 0.74 MMP2 (0.46) CCR2CA2BCAT1
SCHEMBL5745033 0.74 MMP13 (0.52) CCR2CA2MMP13
SCHEMBL28216033 0.74 MMP13 (0.49) CCR2CA2MMP13
SCHEMBL28079462 0.73 MMP13 (0.53) CCR2CA2MMP13
SCHEMBL1924632 0.73 CA2 (0.47) CCR2CA2MMP13
SCHEMBL8232257 0.73 CA2 (0.61) CCR2CA2BCAT1
SCHEMBL16002891 0.73 CA2 (0.61) CCR2CA2
SCHEMBL16985239 0.72 ALDH1A1 (0.55) CCR2CA2BCAT1MEN1KMT2A
SCHEMBL18223966 0.72 ALDH1A1 (0.56) CCR2CA2MMP13BCAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105919987-B N-acyloxysulfonamide and N-hydroxy-N-acylsulfonamide derivatives and uses thereof 约翰斯霍普金斯大学 2020-04-03 CN disclosed
EP-2509941-A2 N-ACYLATED HYDROXYLAMINE DERIVATIVES AND O-ACYLATED HYDROXYLAMINE DERIVATIVES The Johns Hopkins University (US) 2012-10-17 EP disclosed
WO-2011071951-A2 N-ACYLOXYSULFONAMIDE AND N-HYDROXY-N-ACYLSULFONAMIDE DERIVATIVES JOHNS HOPKINS UNIVERSITY (US) 2011-06-16 WO disclosed