Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | CCR2 | P41597 | 12/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10534704 | 0.77 | CA2 (0.58) | CCR2CA2 | |
| SCHEMBL28216033 | 0.77 | MMP13 (0.49) | MMP13CCR2CA2KDM4EALDH1A1 | |
| SCHEMBL1924632 | 0.76 | CA2 (0.47) | MMP13CCR2CA2KDM4EALDH1A1 | |
| SCHEMBL8605861 | 0.75 | MAOB (0.48) | CA12CA1KDM4EALDH1A1HPGD | |
| SCHEMBL1925256 | 0.74 | CA2 (0.50) | MMP13CCR2CA2CA12KDM4E | |
| SCHEMBL9895812 | 0.74 | ACACB (0.61) | CA12CA1CA7CA14ALDH1A1 | |
| SCHEMBL16002891 | 0.74 | CA2 (0.61) | CCR2CA2 | |
| SCHEMBL8232257 | 0.74 | CA2 (0.61) | CCR2CA2HPGD | |
| SCHEMBL1924635 | 0.73 | CCR2 (0.46) | MMP13CCR2CA2 | |
| SCHEMBL21822187 | 0.73 | KDM4E (0.43) | CA2CA12CA1CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105919987-A | N-acyloxysulfonamide And N-hydroxy-n-acylsulfonamide Derivatives And Use Thereof | 约翰斯霍普金斯大学 | 2016-09-07 | — | — | CN | disclosed |
| CN-102753520-B | N-acyloxysulfonamide and N-hydroxy-N-acylsulfonamide derivatives | 约翰斯霍普金斯大学 | 2016-06-08 | — | — | CN | disclosed |