Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 14/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28079462 | 0.77 | MMP13 (0.53) | MMP13CCR2CA2KDM4EALDH1A1 | |
| SCHEMBL1926052 | 0.77 | MMP2 (0.56) | CCR2CA2ALDH1A1HPGD | |
| SCHEMBL1924635 | 0.74 | CCR2 (0.46) | MMP13CCR2CA2 | |
| SCHEMBL1924632 | 0.70 | CA2 (0.47) | MMP13CCR2CA2KDM4EALDH1A1 | |
| SCHEMBL16985239 | 0.70 | ALDH1A1 (0.55) | CCR2CA2KDM4EALDH1A1HPGD | |
| SCHEMBL4846244 | 0.69 | MMP2 (0.46) | CCR2CA2ALDH1A1 | |
| SCHEMBL3608441 | 0.69 | MMP2 (0.74) | MMP13KDM4EALDH1A1 | |
| SCHEMBL1926842 | 0.68 | MMP13 (0.44) | MMP13CCR2CA2ALDH1A1HPGD | |
| SCHEMBL1925256 | 0.68 | CA2 (0.50) | MMP13CCR2CA2KDM4EALDH1A1 | |
| SCHEMBL7299158 | 0.68 | ACACB (0.60) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130855-B | Succinylated hydroxy amine derivatives and application thereof | 约翰斯霍普金斯大学 | 2018-05-25 | — | — | CN | disclosed |