Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 8/20 | 0.51 |
| ▸ | GPR68 | Q15743 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536394 | 0.82 | KCNH3 (0.52) | KCNH3GPR68APPHTR2CHTR7 | |
| SCHEMBL29167130 | 0.77 | CA1 (0.57) | KCNH3GPR68APPNPSR1CA1 | |
| SCHEMBL29223873 | 0.75 | CA1 (0.60) | KCNH3GPR68APPNPSR1CA1 | |
| SCHEMBL1923563 | 0.69 | KCNH3 (0.97) | KCNH3 | |
| SCHEMBL1282106 | 0.68 | ALDH1A1 (0.50) | NPSR1 | |
| SCHEMBL5998625 | 0.67 | KCNH3 (0.68) | KCNH3NPSR1 | |
| SCHEMBL15721117 | 0.67 | HTR7 (0.46) | KCNH3CA1CA2CA9ADRA1D | |
| SCHEMBL17173044 | 0.66 | KCNH3 (0.51) | KCNH3GPR68APPNPSR1CA1 | |
| SCHEMBL14869452 | 0.65 | NPSR1 (0.59) | GPR68APPNPSR1CA1CA2 | |
| SCHEMBL15720926 | 0.64 | HTR7 (0.44) | KCNH3CA1CA2CA9ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479397-B1 | 2,4,6-TRIAMINO-1,3,5-TRIAZINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2011-06-08 | — | — | EP | claimed |