Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19252631 | 0.85 | PIK3CD (0.42) | PIK3CDPIK3R1LMNATP53POLB | |
| SCHEMBL19252627 | 0.77 | PIK3R1 (0.45) | PIK3CDPIK3R1GRM4 | |
| SCHEMBL19252633 | 0.75 | SLC40A1 (0.37) | PIK3CDPIK3R1LMNATP53GRM4 | |
| SCHEMBL19252679 | 0.74 | LMNA (0.33) | LMNATP53CYP1A2POLBCYP3A4 | |
| SCHEMBL19251432 | 0.72 | LMNA (0.33) | LMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL19252635 | 0.71 | PIK3R1 (0.48) | PIK3CDPIK3R1POLBALDH1A1 | |
| SCHEMBL19252639 | 0.68 | PIK3R1 (0.41) | PIK3CDPIK3R1 | |
| SCHEMBL14627845 | 0.68 | CA9 (0.42) | LMNATP53POLBALDH1A1 | |
| SCHEMBL8623459 | 0.68 | NPC1 (0.36) | PIK3CDCYP3A4KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL19252985 | 0.65 | SIRT3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |