Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19251615 | 0.78 | PIK3CD (0.33) | — | |
| SCHEMBL19251425 | 0.75 | LMNA (0.36) | LMNATP53POLBELANE | |
| SCHEMBL19252678 | 0.74 | PIK3CD (0.34) | LMNATP53CYP1A2POLBCYP3A4 | |
| SCHEMBL19251618 | 0.71 | GAA (0.41) | LMNAPOLB | |
| SCHEMBL19251605 | 0.70 | LMNA (0.34) | LMNATP53 | |
| SCHEMBL19251435 | 0.70 | GRIA2 (0.32) | — | |
| SCHEMBL19251433 | 0.69 | PIK3R1 (0.36) | — | |
| SCHEMBL19252612 | 0.65 | CA2 (0.32) | — | |
| SCHEMBL19252627 | 0.64 | PIK3R1 (0.45) | — | |
| SCHEMBL19252631 | 0.62 | PIK3CD (0.42) | LMNATP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133655-A1 | BENZOTHIAZINE AND BENZOTHIADIAZINE COMPOUNDS AND PREPARATION AND USE | 浙江大学 | 2017-08-10 | — | — | WO | disclosed |