Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.68 |
| ▸ | F2R | P25116 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | METAP2 | P50579 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5595491 | 0.88 | ALDH1A1 (0.71) | BCAT2ALDH1A1ADRB2F2RHPGD | |
| SCHEMBL27348350 | 0.86 | LMNA (0.66) | BCAT2ALDH1A1ADRB2F2RMEN1 | |
| SCHEMBL28244196 | 0.86 | HPGD (0.60) | BCAT2ALDH1A1ADRB2F2RHPGD | |
| SCHEMBL1193435 | 0.85 | BCAT2 (0.72) | BCAT2ALDH1A1ADRB2HPGDCYP3A4 | |
| SCHEMBL6271944 | 0.85 | ALDH1A1 (0.68) | BCAT2ALDH1A1ADRB2F2RHPGD | |
| SCHEMBL3744047 | 0.84 | ALDH1A1 (0.66) | BCAT2ALDH1A1ADRB2F2RHPGD | |
| SCHEMBL18397802 | 0.84 | BCAT2 (0.70) | BCAT2ALDH1A1ADRB2HPGDCYP3A4 | |
| SCHEMBL27819009 | 0.84 | BCAT2 (0.70) | BCAT2ALDH1A1ADRB2F2RHPGD | |
| SCHEMBL8971238 | 0.82 | ALDH1A1 (0.73) | BCAT2ALDH1A1ADRB2HPGDCYP3A4 | |
| SCHEMBL1072315 | 0.82 | ALDH1A1 (0.73) | BCAT2ALDH1A1ADRB2HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365588-A1 | DIOL DESYMMETRIZATION BY NUCLEOPHILIC AROMATIC SUBSTITUTION | AMGEN INC. (US) | 2023-11-16 | — | — | US | disclosed |
| EP-3672938-A1 | COMPOSITIONS AND METHODS FOR AMELIORATING PAIN | The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (US) | 2020-07-01 | — | — | EP | disclosed |
| WO-2019040122-A1 | COMPOSITIONS AND METHODS FOR AMELIORATING PAIN | THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2019-02-28 | — | — | WO | disclosed |
| EP-3416954-A1 | A PROCESS FOR THE PREPARATION OF PROPYLENE OXIDE | BASF SE (DE) | 2018-12-26 | — | — | EP | disclosed |
| WO-2017140774-A1 | A PROCESS FOR THE PREPARATION OF PROPYLENE OXIDE | BASF SE (DE) | 2017-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365588-A1 | DIOL DESYMMETRIZATION BY NUCLEOPHILIC AROMATIC SUBSTITUTION | MCL1, BAK1, BCL2A1 | BCAT2 3581/4885ALDH1A1 393/4885ADRB2 2300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.