Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | F2R | P25116 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | METAP2 | P50579 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19259498 | 0.86 | BCAT2 (0.72) | HPGDBCAT2ALDH1A1ADRB2F2R | |
| SCHEMBL4138863 | 0.81 | HPGD (0.77) | HPGDBCAT2ALDH1A1MEN1KMT2A | |
| SCHEMBL27656366 | 0.80 | P2RX7 (0.50) | HPGDALDH1A1F2RHTTKDM4E | |
| SCHEMBL18190481 | 0.79 | MEN1 (0.72) | HPGDBCAT2ALDH1A1MEN1KMT2A | |
| SCHEMBL5595491 | 0.79 | ALDH1A1 (0.71) | HPGDBCAT2ALDH1A1ADRB2F2R | |
| SCHEMBL622225 | 0.77 | CLCN2 (0.54) | HPGDALDH1A1MEN1KMT2AHTT | |
| Benzene SCHEMBL28861692 | 0.77 | CLCN2 (0.54) | HPGDALDH1A1MEN1KMT2AHTT | |
| SCHEMBL7067826 | 0.77 | MEN1 (0.71) | HPGDBCAT2ALDH1A1ADRB2MEN1 | |
| SCHEMBL13862488 | 0.77 | GABRA1 (0.46) | HPGDALDH1A1F2RHTTKDM4E | |
| SCHEMBL7764478 | 0.77 | HPGD (0.74) | HPGDBCAT2ALDH1A1F2RMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473429-A | ROR gamma modulators | 领先制药控股公司 | 2018-08-31 | — | — | CN | disclosed |