Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19265647 | 0.88 | PRKCZ (0.37) | ADORA3ALDH1A1TRPV1 | |
| SCHEMBL19265526 | 0.86 | TLR8 (0.40) | TLR8TLR7ADORA3CA12CA1 | |
| SCHEMBL19265548 | 0.84 | LMNA (0.36) | TLR8TLR7ADORA3KDM4EALDH1A1 | |
| SCHEMBL19265523 | 0.84 | TLR8 (0.35) | TLR8TLR7CA12CA1CA2 | |
| SCHEMBL19265638 | 0.83 | KDM4E (0.36) | TLR8TLR7CA12CA1CA2 | |
| SCHEMBL19265705 | 0.83 | FDFT1 (0.38) | TLR8TLR7CA12CA1CA2 | |
| SCHEMBL19265644 | 0.81 | MMP2 (0.41) | TLR8TLR7ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL19265650 | 0.81 | KDM4E (0.39) | TLR8TLR7KDM4EALDH1A1MAPT | |
| SCHEMBL19265546 | 0.80 | TLR8 (0.33) | TLR8TLR7KDM4EALDH1A1MAPT | |
| SCHEMBL19265655 | 0.77 | HPGD (0.35) | TLR8TLR7KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3208263-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VentiRx Pharmaceuticals, Inc. (US) | 2017-08-23 | — | — | EP | disclosed |