Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19265526 | 0.88 | TLR8 (0.40) | HTTADORA3MEN1ALDH1A1KMT2A | |
| SCHEMBL19265541 | 0.88 | PPARA (0.33) | ADORA3ALDH1A1TRPV1 | |
| SCHEMBL19265548 | 0.86 | LMNA (0.36) | PGRADORA3MEN1ALDH1A1CYP2C9 | |
| SCHEMBL19265650 | 0.86 | KDM4E (0.39) | MEN1ALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL19265523 | 0.85 | TLR8 (0.35) | MEN1ALDH1A1KMT2A | |
| SCHEMBL19265705 | 0.84 | FDFT1 (0.38) | HTTMEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL19265638 | 0.84 | KDM4E (0.36) | ALOX5ALDH1A1 | |
| SCHEMBL19265644 | 0.83 | MMP2 (0.41) | ALOX5ALDH1A1 | |
| SCHEMBL19265546 | 0.81 | TLR8 (0.33) | MEN1ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL19265535 | 0.79 | PRKCZ (0.35) | PRKCZPGRHTTDHFRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3208263-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VentiRx Pharmaceuticals, Inc. (US) | 2017-08-23 | — | — | EP | disclosed |