Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19265647 | 0.86 | PRKCZ (0.37) | CYP2C9MEN1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL19265526 | 0.85 | TLR8 (0.40) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL19265541 | 0.84 | PPARA (0.33) | MAPTALDH1A1GAAKDM4ESLC6A3 | |
| SCHEMBL19265523 | 0.84 | TLR8 (0.35) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL19265705 | 0.83 | FDFT1 (0.38) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL19265638 | 0.83 | KDM4E (0.36) | ALDH1A1GAAKDM4ETSHRTLR8 | |
| SCHEMBL19265650 | 0.82 | KDM4E (0.39) | MAPTCYP2C9MEN1KMT2ACYP3A4 | |
| SCHEMBL19265644 | 0.81 | MMP2 (0.41) | ALDH1A1HSD17B10HPGDCDC7DBF4 | |
| SCHEMBL19265546 | 0.80 | TLR8 (0.33) | MAPTMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL19265651 | 0.79 | GRM6 (0.41) | LMNAMAPTCYP2C9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3208263-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | VentiRx Pharmaceuticals, Inc. (US) | 2017-08-23 | — | — | EP | disclosed |