Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.67 |
| ▸ | SQLE | Q14534 | 7/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | FNTA | P49354 | 1/20 | 0.53 |
| ▸ | FNTB | P49356 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5576405 | 1.00 | KMT2A (0.76) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL27099651 | 1.00 | KMT2A (0.76) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL10014861 | 0.97 | KMT2A (0.71) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL10777183 | 0.97 | KMT2A (0.71) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL2016647 | 0.97 | KMT2A (0.71) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL23802597 | 0.87 | KMT2A (1.00) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| Squalene SCHEMBL890053 | 0.87 | KMT2A (1.00) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL8013144 | 0.87 | KMT2A (1.00) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| Squalene SCHEMBL21823197 | 0.87 | KMT2A (1.00) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL21639794 | 0.87 | KMT2A (1.00) | KMT2AMAPTMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400529-A1 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF MITOCHONDRIAL DISEASE, INCLUDING FRIEDREICH'S ATAXIA | STEALTH BIOTHERAPEUTICS INC. (US) | 2024-12-05 | — | — | US | disclosed |
| US-12049455-B2 | Compositions and methods for the prevention and/or treatment of mitochondrial disease, including Friedreich's ataxia | STEALTH BIOTHERAPEUTICS INC. (US) | 2024-07-30 | — | — | US | disclosed |
| US-11802100-B2 | Olefins and methods for making the same | Amyris, Inc. (US) | 2023-10-31 | — | — | US | disclosed |
| US-20230303506-A1 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF MITOCHONDRIAL DISEASE, INCLUDING FRIEDREICH'S ATAXIA | STEALTH BIOTHERAPEUTICS INC. (US) | 2023-09-28 | — | — | US | disclosed |
| US-20220154092-A1 | OLEFINS AND METHODS FOR MAKING THE SAME | EUAGORE, LLC | 2022-05-19 | — | — | US | disclosed |
| US-11193078-B2 | Olefins and methods for making the same | Amyris, Inc. (US) | 2021-12-07 | — | — | US | disclosed |
| WO-2021243171-A1 | METHODS OF SYNTHESIZING FARNESYL DIBENZODIAZEPINONES | AMO PHARMA LTD (US) | 2021-12-02 | — | — | WO | disclosed |
| EP-3330252-B1 | ISOPRENYL COMPOUNDS AND METHODS THEREOF | SIGNUM BIOSCIENCES INC (US) | 2020-02-12 | — | — | EP | disclosed |
| US-20190249101-A1 | OLEFINS AND METHODS FOR MAKING THE SAME | EUAGORE, LLC | 2019-08-15 | — | — | US | disclosed |
| WO-2017143106-A1 | COMPOSITIONS AND METHODS FOR TREATING LIVER CANCER | GOLDEN BIOTECHNOLOGY CORPORATION (US) | 2017-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190249101-A1 | OLEFINS AND METHODS FOR MAKING THE SAME | HSD17B10, DHCR7, HSD17B12 | KMT2A 2965/4885MAPT 3763/4885MEN1 2665/4885 |
| US-11193078-B2 | Olefins and methods for making the same | HSD17B10, DHCR7, HSD17B12 | KMT2A 2965/4885MAPT 3763/4885MEN1 2665/4885 |
| US-20230303506-A1 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF MITOCHONDRIAL DISEASE, INCLUDING FRIEDREICH'S ATAXIA | FH, COQ8A, TFAM | KMT2A 2420/4885MAPT 1057/4885MEN1 4392/4885 |
| US-20220154092-A1 | OLEFINS AND METHODS FOR MAKING THE SAME | HSD17B10, DHCR7, HSD17B12 | KMT2A 2865/4885MAPT 3808/4885MEN1 2680/4885 |
| US-11802100-B2 | Olefins and methods for making the same | HSD17B10, DHCR7, HSD17B12 | KMT2A 2865/4885MAPT 3808/4885MEN1 2680/4885 |
| US-20240400529-A1 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND/OR TREATMENT OF MITOCHONDRIAL DISEASE, INCLUDING FRIEDREICH'S ATAXIA | FH, COQ8A, TFAM | KMT2A 2420/4885MAPT 1057/4885MEN1 4392/4885 |
| US-12049455-B2 | Compositions and methods for the prevention and/or treatment of mitochondrial disease, including Friedreich's ataxia | FH, COQ8A, TFAM | KMT2A 2420/4885MAPT 1057/4885MEN1 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.