Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.51 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22326402 | 0.86 | SIGMAR1 (0.46) | SIGMAR1GBA1MEN1KMT2AL3MBTL1 | |
| SCHEMBL12337636 | 0.81 | MEN1 (0.46) | SIGMAR1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9801642 | 0.76 | SIGMAR1 (0.40) | SIGMAR1GBA1MEN1KMT2AL3MBTL1 | |
| SCHEMBL19604908 | 0.76 | GUSB (0.55) | SIGMAR1GBA1GUSBBCHEGNAI3 | |
| SCHEMBL3428782 | 0.74 | SIGMAR1 (0.38) | SIGMAR1GBA1MEN1KMT2AL3MBTL1 | |
| SCHEMBL7996310 | 0.74 | SIGMAR1 (0.35) | SIGMAR1GUSBGNAI3GNAO1GNAI1 | |
| SCHEMBL9344937 | 0.73 | GNAO1 (0.50) | GBA1GUSBBCHEGNAI3GNAO1 | |
| SCHEMBL5821937 | 0.73 | DRD2 (0.35) | SIGMAR1MEN1KMT2A | |
| SCHEMBL21581299 | 0.73 | GNAI3 (0.61) | GBA1GUSBGNAI3GNAO1GNAI1 | |
| SCHEMBL21081582 | 0.73 | GNAI3 (0.61) | GBA1GUSBGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9744176-B2 | Therapeutic uses of novel thienopyrimidine derivatives | SANOFI (FR) | 2017-08-29 | — | — | US | disclosed |