SCHEMBL19296451

SCHEMBL19296451

c1ccc(-c2ccc(-c3ccc4c(-c5ccc(-n6c7ccccc7c7ccccc76)c6ccccc56)c5ccccc5c(-c5ccccc5)c4c3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
KMT2A Q03164 2/20 0.34
TSPO P30536 1/20 0.34
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
MEN1 O00255 1/20 0.31
APAF1 O14727 1/20 0.31
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
THRB P10828 1/20 0.31
XBP1 P17861 1/20 0.31
PTBP1 P26599 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13433007 0.94 TSPO (0.39) ATML3MBTL1KDM4EALDH1A1KMT2A
SCHEMBL19296448 0.93 PIK3CA (0.40) KMT2AMEN1MAPT
SCHEMBL13433188 0.92 TSPO (0.38) ATML3MBTL1KDM4EALDH1A1KMT2A
SCHEMBL11910778 0.92 KDM4E (0.37) ATML3MBTL1KDM4EALDH1A1KMT2A
SCHEMBL13669436 0.92 KDM4E (0.37) ATML3MBTL1KDM4EALDH1A1KMT2A
SCHEMBL19296462 0.91 TUBB4A (0.34) ATML3MBTL1KDM4EALDH1A1ESR1
SCHEMBL19296447 0.91 RXRA (0.38) KDM4EALDH1A1KMT2ATSPORXRA
SCHEMBL19296465 0.90 ESR1 (0.33) ATML3MBTL1KDM4EALDH1A1KMT2A
SCHEMBL7601639 0.90 KDM4E (0.42) ATML3MBTL1KDM4EALDH1A1KMT2A
SCHEMBL19296466 0.90 ALOX5 (0.39) ATML3MBTL1KDM4EALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10636976-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-04-28 US disclosed
US-20170250346-A1 ORGANIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-08-31 US disclosed
US-20170250346-A1 ORGANIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10636976-B2 Organic compound, light-emitting element, light-emitting device, electronic device, and lighting device TTI1, TTI2, TERF2 ATM 309/4885L3MBTL1 267/4885KDM4E 2570/4885
US-20170250346-A1 ORGANIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE TTI1, TTI2, TERF2 ATM 309/4885L3MBTL1 267/4885KDM4E 2570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.