Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CEL | P19835 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10803371 | 0.83 | PTGDR2 (0.47) | ALDH1A1CELGAA | |
| SCHEMBL2611706 | 0.83 | KMO (0.49) | KMOLMNAHTTACMSDKMT2A | |
| SCHEMBL11327795 | 0.80 | KMO (0.45) | KMOLMNAHTTACMSDKMT2A | |
| SCHEMBL8895442 | 0.80 | KMO (0.53) | KMOHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL9727253 | 0.77 | PTGS2 (0.46) | KMT2AMEN1ALDH1A1CELMAPT | |
| SCHEMBL2746854 | 0.77 | ACMSD (0.38) | KMOLMNAHTTACMSDHDAC4 | |
| SCHEMBL1929125 | 0.76 | KMO (0.39) | KMOLMNAHTTACMSDKMT2A | |
| SCHEMBL28878066 | 0.75 | CEL (0.40) | LMNAHTTCELHSP90AA1 | |
| SCHEMBL31518340 | 0.75 | KMO (0.50) | KMOLMNAHTTACMSDKMT2A | |
| SCHEMBL779608 | 0.74 | KMO (0.47) | KMOLMNAHTTACMSDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956193-B2 | Intramolecular C-H amination with sulfonyl azides | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-06-07 | — | — | US | disclosed |
| US-7956193-B2 | Intramolecular C-H amination with sulfonyl azides | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-06-07 | — | — | US | disclosed |
| US-20100063277-A1 | Intramolecular C-H amination with sulfonyl azides | NATIONAL SCIENCE FOUNDATION | 2010-03-11 | — | — | US | disclosed |
| US-20100063277-A1 | Intramolecular C-H amination with sulfonyl azides | NATIONAL SCIENCE FOUNDATION | 2010-03-11 | — | — | US | disclosed |
| US-20100063277-A1 | Intramolecular C-H amination with sulfonyl azides | NATIONAL SCIENCE FOUNDATION | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063277-A1 | Intramolecular C-H amination with sulfonyl azides | TST, TIMM9, PPOX | KMO 2966/4885LMNA 1960/4885HTT 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.