Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9022771 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRKDM4EMAPT | |
| SCHEMBL6152657 | 0.77 | MAPT (0.50) | ALDH1A1KDM4EPRSS1F2PRSS2 | |
| SCHEMBL11507189 | 0.75 | MAPT (0.55) | ALDH1A1KDM4EPRSS1F2PRSS2 | |
| SCHEMBL4176103 | 0.75 | ADRA2A (0.47) | ALDH1A1TDP1TSHRKDM4EMAPT | |
| SCHEMBL7637421 | 0.74 | MAPT (0.52) | ALDH1A1TDP1TSHRKDM4EMAPT | |
| SCHEMBL2759019 | 0.74 | ALDH1A1 (0.47) | ALDH1A1TDP1TSHRKDM4EMAPT | |
| SCHEMBL271536 | 0.73 | APP (0.50) | ALDH1A1KDM4EMAPTKCNH3CA12 | |
| SCHEMBL10668913 | 0.72 | MAPT (0.53) | ALDH1A1TDP1TSHRKDM4EMAPT | |
| SCHEMBL4668959 | 0.72 | ALDH1A1 (0.42) | ALDH1A1TDP1TSHRKDM4EPRSS1 | |
| SCHEMBL9652234 | 0.71 | ALDH1A1 (0.51) | ALDH1A1TDP1TSHRKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10219994-B2 | Method for the simultaneous permanent shaping and dyeing of keratinic fibers | HENKEL AG & CO. KGAA (DE) | 2019-03-05 | — | — | US | disclosed |
| US-20170252291-A1 | METHOD FOR THE SIMULTANEOUS PERMANENT SHAPING AND DYEING OF KERATINIC FIBERS | HENKEL AG & CO. KGAA (DE) | 2017-09-07 | — | — | US | disclosed |