Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18502936 | 0.79 | ALOX15 (0.46) | ALOX15PRMT3CARM1PRMT6PRMT1 | |
| Hydrochloric Acid SCHEMBL18668753 | 0.78 | ALOX15 (0.44) | ALOX15PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL15837580 | 0.77 | HTR2A (0.36) | HTR2AHTR2C | |
| SCHEMBL4371445 | 0.71 | ALOX15 (0.50) | ALOX15PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL21625313 | 0.71 | HRH3 (0.33) | KCNH2 | |
| SCHEMBL2600354 | 0.71 | — | — | |
| SCHEMBL20715152 | 0.69 | NCF1 (0.31) | HTR2AHTR2C | |
| SCHEMBL22922810 | 0.69 | KEAP1 (0.42) | ALOX15GNAI3GNAO1GNAI1HTR2A | |
| SCHEMBL7923378 | 0.68 | ALDH1A1 (0.46) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL19267939 | 0.68 | GNAI3 (0.48) | ALOX15PRMT3CARM1PRMT6PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2814834-B1 | C-3 CYCLOALKENYL TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY | VIIV HEALTHCARE UK (NO 5) LTD (GB) | 2017-09-13 | — | — | EP | disclosed |