Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 4/20 | 0.49 |
| ▸ | AR | P10275 | 4/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.38 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8518452 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL14283945 | 0.87 | ALDH1A1 (0.61) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL29837461 | 0.81 | ALDH1A1 (0.51) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL6141613 | 0.81 | ALDH1A1 (0.51) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL11417149 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL6653007 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL30973127 | 0.80 | ALDH1A1 (0.60) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL31476366 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL8604696 | 0.78 | ALDH1A1 (0.48) | ALDH1A1HTTPGRARNR3C1 | |
| SCHEMBL31476408 | 0.78 | ALDH1A1 (0.48) | ALDH1A1HTTPGRARNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10684294-B2 | Diarylether-based fluorogenic probes for detection of hypochlorous acid or hydroxyl radical | THE UNIVERSITY OF HONG KONG (HK) | 2020-06-16 | — | — | US | disclosed |
| US-10407436-B2 | Carboxamide-substituted xanthene dyes | AUDAX PRIVATE DEBT LLC, AS AGENT | 2019-09-10 | — | — | US | disclosed |
| US-10407436-B2 | Carboxamide-substituted xanthene dyes | AUDAX PRIVATE DEBT LLC, AS AGENT | 2019-09-10 | — | — | US | disclosed |
| US-10053484-B2 | Heterocycle-substituted xanthene dyes | BIOTIUM, INC. (US) | 2018-08-21 | — | — | US | disclosed |
| US-20170247402-A1 | HETEROCYCLE-SUBSTITUTED XANTHENE DYES | BIOTIUM, INC. | 2017-08-31 | — | — | US | disclosed |
| US-9579402-B2 | Heterocycle-substituted xanthene dyes | BIOTIUM, INC. (US) | 2017-02-28 | — | — | US | disclosed |
| US-20160362418-A1 | CARBOXAMIDE-SUBSTITUTED XANTHENE DYES | AUDAX PRIVATE DEBT LLC, AS AGENT | 2016-12-15 | — | — | US | disclosed |
| US-20160362418-A1 | CARBOXAMIDE-SUBSTITUTED XANTHENE DYES | AUDAX PRIVATE DEBT LLC, AS AGENT | 2016-12-15 | — | — | US | disclosed |
| US-20160312033-A1 | DIARYLETHER-BASED FLUOROGENIC PROBES FOR DETECTION OF HYPOCHLOROUS ACID OR HYDROXYL RADICAL | VERSITECH LIMITED (HK) | 2016-10-27 | — | — | US | disclosed |
| US-20160312033-A1 | DIARYLETHER-BASED FLUOROGENIC PROBES FOR DETECTION OF HYPOCHLOROUS ACID OR HYDROXYL RADICAL | VERSITECH LIMITED (HK) | 2016-10-27 | — | — | US | disclosed |
| EP-2393805-A1 | XANTHENE DYES COMPRISING A SULFONAMIDE GROUP | Biotium Inc. (US) | 2011-12-14 | — | — | EP | disclosed |
| US-20110136201-A1 | HETEROCYCLE-SUBSTITUTED XANTHENE DYES | BIOTIUM, INC. (US) | 2011-06-09 | — | — | US | disclosed |
| WO-2011068569-A1 | HETEROCYCLE-SUBSTITUTED XANTHENE DYES | BIOTIUM, INC. (US) | 2011-06-09 | — | — | WO | disclosed |
| WO-2010091126-A1 | XANTHENE DYES COMPRISING A SULFONAMIDE GROUP | BIOTIUM, INC. (US) | 2010-08-12 | — | — | WO | disclosed |
| US-20100197030-A1 | XANTHENE DYES COMPRISING A SULFONAMIDE GROUP | BIOTIUM, INC. (US) | 2010-08-05 | — | — | US | disclosed |
| EP-0966458-B1 | SULFONATED XANTHENE DERIVATIVES | MOLECULAR PROBES INC (US) | 2003-08-13 | — | — | EP | disclosed |
| US-6130101-A | FLUORESCENT PROBES FOR USE IN BIOLOGICAL SAMPLES | MOLECULAR PROBES, INC. (US) | 2000-10-10 | — | — | US | disclosed |
| US-5994544-A | PRODUCING A 5H-CHROMENO(3,4-F)QUINOLINE | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1999-11-30 | — | — | US | disclosed |
| US-5410053-A | A pyrano-diquinoline addition or condensation anionic polymer as the novel xanthene dyes for dyeing polyacrylonitrile fibers ; colorfastness | BASF AKTIENGESELLSCHAFT (DE) | 1995-04-25 | — | — | US | disclosed |
| EP-0573762-A2 | Rhodamine derivatives | BASF Aktiengesellschaft (DE) | 1993-12-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197030-A1 | XANTHENE DYES COMPRISING A SULFONAMIDE GROUP | XDH, ARSA, STS | ALDH1A1 1449/4885HTT 1324/4885PGR 756/4885 |
| US-20160362418-A1 | CARBOXAMIDE-SUBSTITUTED XANTHENE DYES | XDH, CYBA, CHAT | ALDH1A1 794/4885HTT 1876/4885PGR 2649/4885 |
| US-20170247402-A1 | HETEROCYCLE-SUBSTITUTED XANTHENE DYES | XDH, CCKAR, CCKBR | ALDH1A1 1142/4885HTT 346/4885PGR 259/4885 |
| US-10407436-B2 | Carboxamide-substituted xanthene dyes | XDH, CYBA, CHAT | ALDH1A1 794/4885HTT 1876/4885PGR 2649/4885 |
| US-20160312033-A1 | DIARYLETHER-BASED FLUOROGENIC PROBES FOR DETECTION OF HYPOCHLOROUS ACID OR HYDROXYL RADICAL | HAGH, HADH, FECH | ALDH1A1 334/4885HTT 394/4885PGR 4540/4885 |
| US-10684294-B2 | Diarylether-based fluorogenic probes for detection of hypochlorous acid or hydroxyl radical | HAGH, HADH, FECH | ALDH1A1 334/4885HTT 394/4885PGR 4540/4885 |
| US-20110136201-A1 | HETEROCYCLE-SUBSTITUTED XANTHENE DYES | XDH, CCKAR, CCKBR | ALDH1A1 1142/4885HTT 346/4885PGR 259/4885 |
| US-10053484-B2 | Heterocycle-substituted xanthene dyes | XDH, CCKAR, CCKBR | ALDH1A1 1142/4885HTT 346/4885PGR 259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.