Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 9/20 | 0.48 |
| ▸ | AR | P10275 | 8/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604696 | 0.89 | ALDH1A1 (0.48) | ALDH1A1RAB9AMEN1USP2TP53 | |
| SCHEMBL11431954 | 0.85 | ALDH1A1 (0.46) | ALDH1A1RAB9AMEN1USP2TP53 | |
| SCHEMBL6141613 | 0.80 | ALDH1A1 (0.51) | ALDH1A1RAB9AMEN1USP2TP53 | |
| SCHEMBL8518452 | 0.79 | ALDH1A1 (0.50) | ALDH1A1RAB9AMEN1USP2TP53 | |
| SCHEMBL6653007 | 0.79 | ALDH1A1 (0.50) | ALDH1A1RAB9AMEN1USP2TP53 | |
| SCHEMBL11417149 | 0.79 | ALDH1A1 (0.50) | ALDH1A1RAB9AMEN1USP2TP53 | |
| SCHEMBL1934505 | 0.79 | ALDH1A1 (0.50) | ALDH1A1RAB9AMEN1USP2TP53 | |
| SCHEMBL30973127 | 0.79 | ALDH1A1 (0.60) | ALDH1A1RAB9AMEN1USP2TP53 | |
| SCHEMBL10840878 | 0.76 | ALDH1A1 (0.58) | ALDH1A1RAB9AMEN1USP2TP53 | |
| SCHEMBL31476408 | 0.76 | ALDH1A1 (0.48) | ALDH1A1RAB9AMEN1USP2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260015335-A1 | AMINE-SUBSTITUTED FLUORESCENT COMPOUNDS | HUGHES HOWARD MED INST (US) | 2026-01-15 | — | — | US | disclosed |
| US-20260001857-A1 | FLUORINATED FLUORESCENT COMPOUNDS | HUGHES HOWARD MED INST (US) | 2026-01-01 | — | — | US | disclosed |
| US-20250282744-A1 | RED-SHIFTED FLUOROPHORES | HOWARD HUGHES MEDICAL INSTITUTE | 2025-09-11 | — | — | US | disclosed |
| US-12344594-B2 | Red-shifted fluorophores | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2025-07-01 | — | — | US | disclosed |
| US-20250115628-A1 | FLUORINATED FLUOROPHORES | HOWARD HUGHES MEDICAL INSTITUTE | 2025-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12344594-B2 | Red-shifted fluorophores | TFEB, DDX21, CDC73 | ALDH1A1 1847/4885RAB9A 465/4885MEN1 2031/4885 |
| US-20250282744-A1 | RED-SHIFTED FLUOROPHORES | TFEB, DDX21, CDC73 | ALDH1A1 1850/4885RAB9A 465/4885MEN1 2030/4885 |
| US-20260001857-A1 | FLUORINATED FLUORESCENT COMPOUNDS | MSN, CHN2, EFHD2 | ALDH1A1 3618/4885RAB9A 329/4885MEN1 1983/4885 |
| US-20260015335-A1 | AMINE-SUBSTITUTED FLUORESCENT COMPOUNDS | AOC2, H1-2, CHAT | ALDH1A1 2761/4885RAB9A 1568/4885MEN1 3103/4885 |
| US-20250115628-A1 | FLUORINATED FLUOROPHORES | PFAS, FLI1, ARFGEF1 | ALDH1A1 1109/4885RAB9A 522/4885MEN1 835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.