Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 11/20 | 0.45 |
| ▸ | AMPD2 | Q01433 | 2/20 | 0.44 |
| ▸ | EP300 | Q09472 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5654147 | 0.95 | TNF (0.46) | TNF | |
| SCHEMBL4230415 | 0.89 | FPR2 (0.46) | TNFALDH1A1 | |
| SCHEMBL25425924 | 0.85 | AMPD2 (0.41) | TNFAMPD2ALDH1A1TSHRFAAH | |
| SCHEMBL16607297 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL25550060 | 0.80 | TNF (0.45) | TNFAMPD2EP300FAAH | |
| SCHEMBL27968084 | 0.79 | TLR8 (0.56) | ALDH1A1TDP1FAAH | |
| SCHEMBL27968082 | 0.79 | TLR8 (0.56) | ALDH1A1TDP1FAAH | |
| SCHEMBL9535005 | 0.79 | TLR8 (0.56) | ALDH1A1TDP1FAAH | |
| SCHEMBL27968081 | 0.79 | TLR8 (0.56) | ALDH1A1TDP1FAAH | |
| SCHEMBL11669837 | 0.79 | TLR8 (0.56) | ALDH1A1TDP1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10053484-B2 | Heterocycle-substituted xanthene dyes | BIOTIUM, INC. (US) | 2018-08-21 | — | — | US | disclosed |
| US-20170247402-A1 | HETEROCYCLE-SUBSTITUTED XANTHENE DYES | BIOTIUM, INC. | 2017-08-31 | — | — | US | disclosed |
| US-20170247402-A1 | HETEROCYCLE-SUBSTITUTED XANTHENE DYES | BIOTIUM, INC. | 2017-08-31 | — | — | US | disclosed |
| US-20170247402-A1 | HETEROCYCLE-SUBSTITUTED XANTHENE DYES | BIOTIUM, INC. | 2017-08-31 | — | — | US | disclosed |
| US-9579402-B2 | Heterocycle-substituted xanthene dyes | BIOTIUM, INC. (US) | 2017-02-28 | — | — | US | disclosed |
| US-9579402-B2 | Heterocycle-substituted xanthene dyes | BIOTIUM, INC. (US) | 2017-02-28 | — | — | US | disclosed |
| US-9579402-B2 | Heterocycle-substituted xanthene dyes | BIOTIUM, INC. (US) | 2017-02-28 | — | — | US | disclosed |
| EP-2507220-B1 | HETEROCYCLE-SUBSTITUTED XANTHENE DYES | BIOTIUM INC (US) | 2016-10-05 | — | — | EP | disclosed |
| EP-2507220-B1 | HETEROCYCLE-SUBSTITUTED XANTHENE DYES | BIOTIUM INC (US) | 2016-10-05 | — | — | EP | disclosed |
| EP-2507220-A1 | HETEROCYCLE-SUBSTITUTED XANTHENE DYES | Biotium Inc. (US) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011068569-A1 | HETEROCYCLE-SUBSTITUTED XANTHENE DYES | BIOTIUM, INC. (US) | 2011-06-09 | — | — | WO | disclosed |
| US-20110136201-A1 | HETEROCYCLE-SUBSTITUTED XANTHENE DYES | BIOTIUM, INC. (US) | 2011-06-09 | — | — | US | disclosed |
| WO-2011068569-A1 | HETEROCYCLE-SUBSTITUTED XANTHENE DYES | BIOTIUM, INC. (US) | 2011-06-09 | — | — | WO | disclosed |
| US-20110136201-A1 | HETEROCYCLE-SUBSTITUTED XANTHENE DYES | BIOTIUM, INC. (US) | 2011-06-09 | — | — | US | disclosed |
| US-20110136201-A1 | HETEROCYCLE-SUBSTITUTED XANTHENE DYES | BIOTIUM, INC. (US) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170247402-A1 | HETEROCYCLE-SUBSTITUTED XANTHENE DYES | XDH, CCKAR, CCKBR | TNF 926/4885AMPD2 2479/4885EP300 3441/4885 |
| US-20110136201-A1 | HETEROCYCLE-SUBSTITUTED XANTHENE DYES | XDH, CCKAR, CCKBR | TNF 926/4885AMPD2 2479/4885EP300 3441/4885 |
| US-10053484-B2 | Heterocycle-substituted xanthene dyes | XDH, CCKAR, CCKBR | TNF 926/4885AMPD2 2479/4885EP300 3441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.