Sugi Predict

Sugi Predict / Compounds / SCHEMBL19358

SCHEMBL19358

SCHEMBL19358

C[C]1C=Cc2ccccc2N1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.68
▸ GAA P10253 2/20 0.68
▸ RAB9A P51151 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ P2RX4 Q99571 1/20 0.39
▸ CA12 O43570 1/20 0.34
▸ CA1 P00915 1/20 0.34
▸ CA2 P00918 1/20 0.34
▸ CA9 Q16790 1/20 0.34
▸ ACHE P22303 3/20 0.33
▸ ALOX12 P18054 2/20 0.33
▸ LMNA P02545 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ ALDH1A1 P00352 2/20 0.32
▸ CYP3A4 P08684 2/20 0.32
▸ TDP1 Q9NUW8 2/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ MEN1 O00255 2/20 0.31
▸ KMT2A Q03164 2/20 0.31
▸ KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iminostilbene SCHEMBL75288 0.82 MAPT (1.00) MAPTGAARAB9ASMN1; SMN2P2RX4
Iminostilbene SCHEMBL29926907 0.82 MAPT (1.00) MAPTGAARAB9ASMN1; SMN2P2RX4
Iminostilbene SCHEMBL5063042 0.79 MAPT (0.94) MAPTGAARAB9ASMN1; SMN2P2RX4
Iminostilbene SCHEMBL9685179 0.79 MAPT (0.94) MAPTGAARAB9ASMN1; SMN2P2RX4
SCHEMBL16131316 0.74 MAPT (0.58) MAPTGAARAB9ASMN1; SMN2P2RX4
SCHEMBL30285272 0.74 MAPT (0.64) MAPTGAARAB9ASMN1; SMN2P2RX4
SCHEMBL20968079 0.74 MAPT (0.64) MAPTGAARAB9ASMN1; SMN2P2RX4
SCHEMBL6307596 0.74 MAPT (0.58) MAPTGAARAB9ASMN1; SMN2P2RX4
SCHEMBL13319519 0.73 MAPT (0.62) MAPTGAARAB9ASMN1; SMN2P2RX4
SCHEMBL12698229 0.73 MAPT (0.61) MAPTGAARAB9ASMN1; SMN2P2RX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 740 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9231219-B2 N-doping of organic semiconductors by bis-metallosandwich compounds GEORGIA TECH RESEARCH CORPORATION (US) 2016-01-05 — — US claimed
US-20140302635-A1 N-DOPING OF ORGANIC SEMICONDUCTORS BY BIS-METALLOSANDWICH COMPOUNDS THE TRUSTEES OF PRINCETON UNIVERSITY 2014-10-09 — — US claimed
EP-2721658-A1 N-DOPING OF ORGANIC SEMICONDUCTORS BY BIS-METALLOSANDWICH COMPOUNDS Georgia Tech Research Corporation (US) 2014-04-23 — — EP claimed
WO-2013055410-A9 N-DOPING OF ORGANIC SEMICONDUCTORS BY BIS-METALLOSANDWICH COMPOUNDS GEORGIA TECH RESEARCH CORPORATION (US) 2013-07-11 — — WO claimed
WO-2013055410-A1 N-DOPING OF ORGANIC SEMICONDUCTORS BY BIS-METALLOSANDWICH COMPOUNDS GEORGIA TECH RESEARCH CORPORATION (US) 2013-04-18 — — WO claimed
EP-0476456-B1 Substituted 2-thiazolyl tetrazolium salt indicators BAYER AG (US) 1997-11-12 — — EP claimed
EP-0476454-B1 Analytical method using tetrazolium salt indicators having a reflectance plateau BAYER AG (US) 1996-10-23 — — EP claimed
US-5322680-A Chromogenic detector for medical diagnosis by forming formazan dyes chemical reduction MILES INC. (US) 1994-06-21 — — US claimed
US-5126275-A Chromogenic reducing indicators for reducing substances such as NADH MILES INC. (US) 1992-06-30 — — US claimed
EP-0476454-A1 Analytical method using tetrazolium salt indicators having a reflectance plateau Bayer Corporation (US) 1992-03-25 — — EP claimed
EP-0476457-A2 2-Benzothiazolyl tetrazolium salt indicators Bayer Corporation (US) 1992-03-25 — — EP claimed
EP-0476456-A2 Substituted 2-thiazolyl tetrazolium salt indicators Bayer Corporation (US) 1992-03-25 — — EP claimed
EP-0476455-A2 Phenyl-substituted 2-thiazolyl tetrazolium salt indicators Bayer Corporation (US) 1992-03-25 — — EP claimed
US-12029796-B2 Fluorescent probes for silver ION detection THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2024-07-09 — — US disclosed
US-12024518-B1 Pyrazolo[4,3-C][1,6]naphthyridines as CK2 inhibitors King Faisal University (SA) 2024-07-02 — — US disclosed
US-12023387-B2 NIR-II emissive luminogens THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2024-07-02 — — US disclosed
EP-0476454-A1 Analytical method using tetrazolium salt indicators having a reflectance plateau Bayer Corporation (US) 1992-03-25 — — EP disclosed
EP-0476457-A2 2-Benzothiazolyl tetrazolium salt indicators Bayer Corporation (US) 1992-03-25 — — EP disclosed
EP-0476456-A2 Substituted 2-thiazolyl tetrazolium salt indicators Bayer Corporation (US) 1992-03-25 — — EP disclosed
EP-0476455-A2 Phenyl-substituted 2-thiazolyl tetrazolium salt indicators Bayer Corporation (US) 1992-03-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12023387-B2 NIR-II emissive luminogens DBI, UACA, BRI3BP MAPT 471/4885GAA 2375/4885RAB9A 1414/4885
US-12024518-B1 Pyrazolo[4,3-C][1,6]naphthyridines as CK2 inhibitors CSNK2A3, CSNK1A1, CSNK1G3 MAPT 952/4885GAA 1460/4885RAB9A 3142/4885
US-12029796-B2 Fluorescent probes for silver ION detection FUS, APC, ALB MAPT 418/4885GAA 519/4885RAB9A 2552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.