Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19358237 | 1.00 | TRPA1 (0.38) | TRPA1PTGS1CACNA1CALDH1A1ALOX12 | |
| SCHEMBL5693590 | 0.98 | TRPA1 (0.37) | TRPA1PTGS1CACNA1CALDH1A1ALOX12 | |
| SCHEMBL17118293 | 0.76 | LMNA (0.40) | TRPA1PTGS1CACNA1CALDH1A1ALOX12 | |
| SCHEMBL19334606 | 0.76 | LMNA (0.38) | TRPA1PTGS1CACNA1CALDH1A1ALOX12 | |
| SCHEMBL19358010 | 0.75 | KDM4E (0.47) | ALDH1A1ALOX12HTTGAAMAPT | |
| SCHEMBL7646738 | 0.74 | SIGMAR1 (0.54) | PTGS1HIF1ALMNAGABRA1GABRB2 | |
| SCHEMBL7646734 | 0.74 | SIGMAR1 (0.54) | PTGS1HIF1ALMNAGABRA1GABRB2 | |
| SCHEMBL19358130 | 0.73 | NPC1 (0.35) | TRPA1PTGS1CACNA1CGAAMAPT | |
| SCHEMBL7591507 | 0.72 | CYP3A4 (0.38) | TRPA1PTGS1CACNA1CALDH1A1ALOX12 | |
| SCHEMBL778017 | 0.69 | LMNA (0.46) | TRPA1PTGS1CACNA1CALDH1A1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017158469-A1 | METHODS OF MAKING ALPHA, BETA-UNSATURATED CARBOXYLIC ACIDS OR SALTS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-09-21 | — | — | WO | disclosed |