Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19334606 | 0.79 | LMNA (0.38) | LMNAHTTRNASEH1TRPA1PTGS1 | |
| SCHEMBL20306061 | 0.79 | LMNA (0.50) | LMNAHTTTRPA1CHRM1SLC6A2 | |
| SCHEMBL21538604 | 0.79 | LMNA (0.40) | LMNAHTTTRPA1PTGS1MAPT | |
| SCHEMBL7591507 | 0.79 | CYP3A4 (0.38) | LMNAHTTRNASEH1TRPA1PTGS1 | |
| SCHEMBL3285296 | 0.78 | RNASEH1 (0.53) | LMNAHTTRNASEH1TRPA1PTGS1 | |
| SCHEMBL16918736 | 0.78 | TYR (0.42) | LMNAHTTRNASEH1TRPA1PTGS1 | |
| SCHEMBL19358239 | 0.76 | TRPA1 (0.38) | LMNAHTTRNASEH1TRPA1PTGS1 | |
| SCHEMBL19358237 | 0.76 | TRPA1 (0.38) | LMNAHTTRNASEH1TRPA1PTGS1 | |
| SCHEMBL5693590 | 0.75 | TRPA1 (0.37) | LMNAHTTRNASEH1TRPA1PTGS1 | |
| SCHEMBL12812552 | 0.75 | ALDH1A1 (0.38) | LMNAHTTMAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150267232-A1 | IN VIVO AND IN VITRO CARBENE INSERTION AND NITRENE TRANSFER REACTIONS CATALYZED BY HEME ENZYMES | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2015-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150267232-A1 | IN VIVO AND IN VITRO CARBENE INSERTION AND NITRENE TRANSFER REACTIONS CATALYZED BY HEME ENZYMES | HMBS, HMOX1, HMOX2 | LMNA 3091/4885HTT 1172/4885RNASEH1 617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.