Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | CLK2 | P49760 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.38 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19670557 | 0.83 | PIK3CD (0.38) | KMOPIK3CDPIK3CAPIK3CGDHODH | |
| SCHEMBL19670563 | 0.81 | ALOX15 (0.44) | ALOX15TSHRCASP1NPSR1HSD17B10 | |
| SCHEMBL19670289 | 0.79 | BRAF (0.42) | KMOPIK3CDPIK3CAPIK3CGMAP4K4 | |
| SCHEMBL20632322 | 0.78 | ALOX15 (0.41) | ALOX15TSHRCASP1NPSR1HSD17B10 | |
| SCHEMBL20632436 | 0.73 | ALOX15 (0.37) | ALOX15TSHRCASP1NPSR1HSD17B10 | |
| SCHEMBL21841343 | 0.73 | KMO (0.41) | KMOPIK3CDPIK3CAPIK3CGCA2 | |
| SCHEMBL19365461 | 0.73 | HDAC1 (0.39) | ALOX15TSHRCASP1NPSR1HSD17B10 | |
| SCHEMBL20632508 | 0.73 | NPSR1 (0.35) | ALOX15TSHRCASP1NPSR1HSD17B10 | |
| SCHEMBL19670601 | 0.72 | POLB (0.41) | KMOPIK3CDPIK3CAPIK3CGCA2 | |
| SCHEMBL19365619 | 0.72 | KMO (0.37) | ALOX15TSHRCASP1NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9765075-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-09-19 | — | — | US | disclosed |