Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19365489 | 0.83 | ALOX15 (0.48) | PIK3CDPIK3CAPIK3CGKMOCA2 | |
| SCHEMBL19670289 | 0.83 | BRAF (0.42) | PIK3CDPIK3CAPIK3CGKMOCA12 | |
| SCHEMBL19670603 | 0.82 | POLB (0.43) | PIK3CDPIK3CAPIK3CGKMOKIF11 | |
| SCHEMBL19365841 | 0.81 | PIK3CD (0.36) | PIK3CDPIK3CAPIK3CGKMOKIF11 | |
| SCHEMBL19365429 | 0.73 | POLB (0.36) | — | |
| SCHEMBL19706132 | 0.72 | TRPV3 (0.35) | — | |
| SCHEMBL19365509 | 0.72 | PHGDH (0.38) | PIK3CDPIK3CAPIK3CGKMODHODH | |
| SCHEMBL19365519 | 0.71 | POLB (0.46) | KIF11MEN1KMT2AMAPT | |
| SCHEMBL19365506 | 0.70 | UBE2M (0.41) | KIF11FYNMEN1KMT2AMAPT | |
| SCHEMBL19365636 | 0.70 | POLB (0.46) | PIK3CDPIK3CAPIK3CGKMOKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834558-B2 | Substituted bridged urea analogs as sirtuin modulators | GLAXOSMITHKLINE LLC (US) | 2017-12-05 | — | — | US | disclosed |