SCHEMBL19367491

SCHEMBL19367491

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nearest known ligand 0.74

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LGALS3 P17931 8/20 0.74
LGALS8 O00214 2/20 0.74
LGALS4 P56470 2/20 0.74
MAPK1 P28482 1/20 0.58
IGF2R P11717 2/20 0.48
CD69 Q07108 1/20 0.46
CHIA Q9BZP6 1/20 0.45
LGALS1 P09382 1/20 0.45
LGALS7; LGALS7B P47929 1/20 0.45
ALDH1A1 P00352 1/20 0.44
THRB P10828 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
SIGLEC7 Q9Y286 2/20 0.44
LGALS9 O00182 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21852877 1.00 LGALS3 (0.74) LGALS3LGALS8LGALS4MAPK1IGF2R
SCHEMBL21258434 1.00 LGALS3 (0.74) LGALS3LGALS8LGALS4MAPK1IGF2R
SCHEMBL17252078 1.00 LGALS3 (0.74) LGALS3LGALS8LGALS4MAPK1IGF2R
SCHEMBL19197226 1.00 LGALS3 (0.74) LGALS3LGALS8LGALS4MAPK1IGF2R
SCHEMBL21258435 1.00 LGALS3 (0.74) LGALS3LGALS8LGALS4MAPK1IGF2R
SCHEMBL19196654 1.00 LGALS3 (0.74) LGALS3LGALS8LGALS4MAPK1IGF2R
SCHEMBL21851468 0.96 LGALS3 (0.68) LGALS3LGALS8LGALS4MAPK1IGF2R
SCHEMBL19197194 0.96 LGALS3 (0.68) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL19567579 0.96 LGALS3 (0.68) LGALS3LGALS8LGALS4MAPK1CD69
SCHEMBL21851348 0.93 LGALS3 (0.64) LGALS3LGALS8LGALS4MAPK1IGF2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11766483-B2 Compounds and therapeutics uses thereof Centauri Therapeutics Limited (GB/GB) (GB) 2023-09-26 US disclosed
US-11760779-B2 Preparation of ceramide conjugates and derivatives of sphingolipid analogues KODE BIOTECH LIMITED (NZ) 2023-09-19 US disclosed
US-20180057518-A1 SYNTHETIC MEMBRANE ANCHORS KODE BIOTECH LTD. (NZ) 2018-03-01 US disclosed
US-20170320914-A1 MULTIVALENT LIGAND-LIPID CONSTRUCTS BOVIN NICOLAI VLADIMIROVICH (RU) 2017-11-09 US disclosed
US-20170266214-A1 GLYCOLIPID CONTAINING COMPOSITIONS FOR USE IN THE TREATMENT OF TUMOURS KREOS CAPITAL V (EXPERT FUND) L.P. (JE) 2017-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11760779-B2 Preparation of ceramide conjugates and derivatives of sphingolipid analogues SGMS1, SGMS2, CERT1 LGALS3 2038/4885LGALS8 2012/4885LGALS4 2425/4885
US-20180057518-A1 SYNTHETIC MEMBRANE ANCHORS PTDSS2, DDOST, STT3B LGALS3 429/4885LGALS8 541/4885LGALS4 253/4885
US-11766483-B2 Compounds and therapeutics uses thereof MAVS, MYD88, CD47 LGALS3 139/4885LGALS8 156/4885LGALS4 107/4885
US-20170266214-A1 GLYCOLIPID CONTAINING COMPOSITIONS FOR USE IN THE TREATMENT OF TUMOURS LGALS2, LGALS3, LGALS1 LGALS3 2/4885LGALS8 7/4885LGALS4 5/4885
US-20170320914-A1 MULTIVALENT LIGAND-LIPID CONSTRUCTS PHOSPHO1, MGLL, LPAR6 LGALS3 474/4885LGALS8 564/4885LGALS4 424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.