SCHEMBL1936882

SCHEMBL1936882

Nc1cccc(N2CCOC2=O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 1/20 0.51
CRBN Q96SW2 1/20 0.51
KDM1A O60341 3/20 0.47
MAOA P21397 3/20 0.47
MAOB P27338 3/20 0.47
RCOR1 Q9UKL0 3/20 0.47
KDM1B Q8NB78 2/20 0.47
ADRA2C P18825 1/20 0.46
SLC9A3 P48764 1/20 0.44
MAPT P10636 3/20 0.43
GRM2 Q14416 1/20 0.43
TNKS O95271 1/20 0.42
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 1/20 0.41
ALOX15 P16050 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
CAMK1D Q8IU85 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6240554 0.83 SLC9A3 (0.48) KDM1AMAOAMAOBRCOR1KDM1B
SCHEMBL6241946 0.82 KMO (0.51) KDM1AMAOAMAOBRCOR1KDM1B
SCHEMBL6244936 0.82 SLC9A3 (0.47) KDM1AMAOAMAOBRCOR1KDM1B
SCHEMBL12362785 0.81 KDM1A (0.46) KDM1AMAOAMAOBRCOR1KDM1B
SCHEMBL10191867 0.81 HSD11B1 (0.55) MAOAMAOBMAPTGRM2ALDH1A1
SCHEMBL30669251 0.81 FADS1 (0.50) KDM1AMAOAMAOBRCOR1KDM1B
SCHEMBL4004501 0.81 HSD11B1 (0.52) KDM1AMAOAMAOBRCOR1KDM1B
SCHEMBL30669238 0.81 HSD11B1 (0.55) MAOAMAOBMAPTGRM2ALDH1A1
SCHEMBL13853420 0.81 HTR1A (0.46) KDM1AMAOAMAOBRCOR1KDM1B
SCHEMBL15776592 0.81 KDM1A (0.58) KDM1AMAOAMAOBRCOR1KDM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110257033-B Water-based cleaning solution and preparation method and application thereof 中国海洋石油集团有限公司 2021-09-10 CN claimed
US-20240066136-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2024-02-29 US disclosed
US-20240066136-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2024-02-29 US disclosed
CN-117105880-A Urea compounds for inducing antigen-specific reaction, fluorescent markers thereof, preparation method and application 上海康斯维克生物医药有限公司 2023-11-24 CN disclosed
CN-116472292-A Modified proteins and protein degrading agents 上海睿跃生物科技有限公司 2023-07-21 CN disclosed
EP-4157888-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS Cullgen (Shanghai), Inc. (CN) 2023-04-05 EP disclosed
US-20230057177-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI), INC. (CN) 2023-02-23 US disclosed
US-11530193-B2 Kinase inhibitors THE UNIVERSITY OF MANCHESTER (GB) 2022-12-20 US disclosed
WO-2021239117-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS CULLGEN (SHANGHAI) , INC. (CN) 2021-12-02 WO disclosed
CN-110257033-B Water-based cleaning solution and preparation method and application thereof 中国海洋石油集团有限公司 2021-09-10 CN disclosed
EP-3793996-A1 KINASE INHIBITORS The University of Manchester (GB) 2021-03-24 EP disclosed
EP-3008045-B1 ANTIBACTERIAL THIAZOLECARBOXYLIC ACIDS ANTABIO SAS (FR) 2018-05-09 EP disclosed
US-20110245242-A1 Heterocyclically Substituted Anilinopyrimides BAYER CROPSCIENCE AG (DE) 2011-10-06 US disclosed
EP-2331524-A1 HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES Bayer CropScience AG (DE) 2011-06-15 EP disclosed
WO-2010025831-A1 HETEROCYCLICALLY SUBSTITUTED ANILINOPYRIMIDINES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2010-03-11 WO disclosed
WO-2009090548-A2 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS VANILLOID RECEPTOR LIGANDS GLENMARK PHARMACEUTICALS, S.A. (US) 2009-07-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240066136-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS DDB1, DCLRE1A, MDM2 DDB1 1/4885CRBN 92/4885KDM1A 301/4885
US-11530193-B2 Kinase inhibitors CAMKK2, CAMK1, CAMKK1 DDB1 2521/4885CRBN 2406/4885KDM1A 2294/4885
US-20230057177-A1 MODIFIED PROTEINS AND PROTEIN DEGRADERS DDB1, DCLRE1A, MDM2 DDB1 1/4885CRBN 92/4885KDM1A 301/4885
US-20110245242-A1 Heterocyclically Substituted Anilinopyrimides H1-10, POLL, PPM1D DDB1 913/4885CRBN 633/4885KDM1A 442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.