Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29787065 | 0.83 | GAA (0.32) | CHRNB2CHRNA4SIGMAR1CHRNA7CYP2A6 | |
| SCHEMBL1939592 | 0.83 | GAA (0.32) | CHRNB2CHRNA4SIGMAR1CHRNA7CYP2A6 | |
| SCHEMBL993667 | 0.78 | — | — | |
| SCHEMBL35212107 | 0.74 | — | — | |
| Acetic Acid SCHEMBL28280160 | 0.73 | KDM4C (0.33) | — | |
| SCHEMBL29415525 | 0.71 | GAA (0.48) | TNKS2 | |
| SCHEMBL20546040 | 0.71 | CHRNB2 (0.31) | CHRNB2CHRNA4SIGMAR1 | |
| SCHEMBL30365757 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL9047476 | 0.70 | GAA (0.46) | TNKS2 | |
| Potassium SCHEMBL9683518 | 0.70 | GAA (0.46) | TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260124198-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | GILEAD SCIENCES INC (US) | 2026-05-07 | — | — | US | claimed |
| CN-105348282-B | A kind of HIV-1 integrase inhibitor compounds and its preparation method and application | 北京工业大学 | 2018-06-29 | — | — | CN | claimed |
| US-20260124198-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | GILEAD SCIENCES INC (US) | 2026-05-07 | — | — | US | disclosed |
| US-20230174530-A1 | N-(PHENYLAMINOCARBONYL) TETRAHYDRO-ISOQUINOLINES AND RELATED COMPOUNDS AS MODULATORS OF GPR65 | Pathios Therapeutics Limited (GB) | 2023-06-08 | — | — | US | disclosed |
| CN-110156754-A | A kind of inhibiting effect of trisubstituted pyrimidine derivatives to protein kinase | 杭州百诚医药科技股份有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-108617166-A | Protein Kinase Inhibitor Benzolactam Compounds | 大冢制药株式会社 | 2018-10-02 | — | — | CN | disclosed |
| CN-106794161-A | TrkA kinase inhibitors, composition and its method | 默沙东公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-106795147-A | Cyclopropyl fused thiazine-2-amine compounds as beta-secretase inhibitors and methods of use | 美国安进公司 | 2017-05-31 | — | — | CN | disclosed |
| EP-3141542-A1 | SUBSTITUTED BENZALDEHYDE COMPOUNDS AND METHODS FOR THEIR USE IN INCREASING TISSUE OXYGENATION | Global Blood Therapeutics, Inc. (US) | 2017-03-15 | — | — | EP | disclosed |
| CN-103864792-B | Heterocyclic nitrogen compound acting as tyrosine kinase inhibitor | 山东亨利医药科技有限责任公司 | 2017-01-18 | — | — | CN | disclosed |
| WO-2016202898-A1 | GLUCOSE TRANSPORT INHIBITORS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-12-22 | — | — | WO | disclosed |
| US-20110172126-A1 | LIBRARIES OF PEPTIDE CONJUGATES AND METHODS FOR MAKING THEM | XENOME LTD (AU) | 2011-07-14 | — | — | US | disclosed |
| EP-2331561-A1 | LIBRARIES OF PEPTIDE CONJUGATES AND METHODS FOR MAKING THEM | Xenome Ltd (AU) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010025510-A1 | LIBRARIES OF PEPTIDE CONJUGATES AND METHODS FOR MAKING THEM | XENOME LTD (AU) | 2010-03-11 | — | — | WO | disclosed |
| US-20090082358-A1 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. | 2009-03-26 | — | — | US | disclosed |
| US-7291449-B2 | Silver halide photographic material and methine dye | FUJIFILM CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-7291449-B2 | Silver halide photographic material and methine dye | FUJIFILM CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| CN-101039920-A | 2,6-substituted-4-monosubstitutedamino-pyrimidine as prostaglandin d2 receptor antagonists | AVENTIS PHARMA INC (US) | 2007-09-19 | — | — | CN | disclosed |
| EP-0061178-B1 | NOVEL 1,2-DIHYDROPYRIDO(3,4-B)-PYRAZINES AND METHOD FOR PREPARING SAME | Southern Research Institute (US) | 1986-02-26 | — | — | EP | disclosed |
| EP-0061178-A2 | Novel 1,2-dihydropyrido(3,4-b)-pyrazines and method for preparing same | Southern Research Institute (US) | 1982-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260124198-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | ZC3HAV1, CCR1, CCR6 | TNKS2 3400/4885CHRNB2 2036/4885CHRNA4 1363/4885 |
| US-20230174530-A1 | N-(PHENYLAMINOCARBONYL) TETRAHYDRO-ISOQUINOLINES AND RELATED COMPOUNDS AS MODULATORS OF GPR65 | GPR3, GPR65, GPR52 | TNKS2 4608/4885CHRNB2 171/4885CHRNA4 109/4885 |
| US-20090082358-A1 | Vanilloid receptor ligands and their use in treatments | TRPV1, TRPV3, TRPV2 | TNKS2 2115/4885CHRNB2 523/4885CHRNA4 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.