Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22644041 | 0.83 | LTA4H (0.45) | LTA4HALDH1A1SPHK1S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL21724241 | 0.82 | LTA4H (0.51) | LTA4HSPHK1S1PR1S1PR3SPHK2 | |
| Hydrochloric Acid SCHEMBL21724243 | 0.82 | LTA4H (0.51) | LTA4HSPHK1S1PR1S1PR3SPHK2 | |
| SCHEMBL19375764 | 0.80 | SPHK1 (0.49) | LTA4HSPHK1S1PR1S1PR3SPHK2 | |
| SCHEMBL19234502 | 0.79 | CRHBP (0.51) | LTA4HSPHK1S1PR1S1PR3TP53 | |
| SCHEMBL20715719 | 0.76 | SPHK1 (0.59) | SPHK1S1PR1S1PR3SPHK2S1PR4 | |
| SCHEMBL20715718 | 0.76 | GAA (0.55) | LTA4HSPHK1MAPTSPHK2AAK1 | |
| SCHEMBL25863651 | 0.76 | AAK1 (0.56) | LTA4HAAK1LARS1 | |
| SCHEMBL19375763 | 0.75 | HTR2A (0.57) | LTA4HALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6291030 | 0.75 | LTA4H (0.45) | LTA4HSPHK1S1PR1S1PR3SPHK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170266308-A1 | SMALL MOLECULE CONJUGATES SPECIFICALLY ACTIVATED IN TUMOR MICROENVIROMENT FOR TARGETING AND USE THEREOF | YAFEI SHANGHAI BIOLOG MEDICINE SCIENCE & TECHNOLOGY CO. LTD. (CN) | 2017-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170266308-A1 | SMALL MOLECULE CONJUGATES SPECIFICALLY ACTIVATED IN TUMOR MICROENVIROMENT FOR TARGETING AND USE THEREOF | CD4, MET, TNFSF10 | LTA4H 733/4885ALDH1A1 3614/4885SPHK1 2085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.