Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28882768 | 0.77 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL19385386 | 0.77 | MAPT (0.50) | NPSR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4064946 | 0.77 | CDK5 (0.60) | ESR1ESR2CYP19A1MEN1KMT2A | |
| SCHEMBL19385394 | 0.76 | KDM4E (0.51) | NPSR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL19385398 | 0.76 | KDM4E (0.51) | NPSR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7915055 | 0.74 | MEN1 (0.65) | ESR1ESR2CYP19A1NPSR1MEN1 | |
| SCHEMBL7915056 | 0.74 | MEN1 (0.65) | ESR1ESR2CYP19A1NPSR1MEN1 | |
| SCHEMBL28245664 | 0.73 | KIF11 (0.39) | NPSR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10936800 | 0.70 | ESR1 (0.61) | ESR1ESR2CYP19A1NPSR1MEN1 | |
| SCHEMBL29789603 | 0.69 | KIF11 (0.49) | NPSR1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017163263-A1 | INDOLE DERIVATIVES, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-28 | — | — | WO | disclosed |