Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19404 | 1.00 | EP300 (0.31) | EP300 | |
| SCHEMBL14055652 | 1.00 | EP300 (0.31) | EP300 | |
| SCHEMBL15136270 | 0.85 | — | — | |
| SCHEMBL4296539 | 0.84 | EP300 (0.31) | EP300 | |
| SCHEMBL4296542 | 0.84 | EP300 (0.31) | EP300 | |
| SCHEMBL17164585 | 0.83 | — | — | |
| SCHEMBL20248 | 0.83 | NPSR1 (0.44) | — | |
| SCHEMBL19246 | 0.83 | NPSR1 (0.44) | — | |
| SCHEMBL452937 | 0.83 | NPSR1 (0.44) | — | |
| SCHEMBL18936288 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819346-B | Synthesis method of 3- (difluoromethyl) -1-methyl-1H-pyrazole-4-ethyl formate | 湖南化工研究院有限公司 | 2024-09-24 | — | — | CN | claimed |
| CN-114315577-B | Synthesis method of 2-ethoxymethylene-4, 4-difluoro acetoacetic acid ethyl ester | 湖南海利化工股份有限公司 | 2024-09-13 | — | — | CN | claimed |
| CN-117960075-A | Continuous production system and process of 1-methyl-3-difluoromethyl-1H-pyrazole-4-carboxylic acid | 天津凯莱英医药科技发展有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-114957123-B | 3- (difluoromethyl) -pyrazole-4-carboxylic ester derivative and preparation method and application thereof | 浙江工业大学 | 2023-11-28 | — | — | CN | claimed |
| CN-114957123-A | 3- (difluoromethyl) -pyrazole-4-carboxylic ester derivative and preparation method and application thereof | 浙江工业大学 | 2022-08-30 | — | — | CN | claimed |
| WO-2015155713-A1 | PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF 1,3, 4 -SUBSTITUTED PYRAZOLES | ISAGRO S.P.A. (IT) | 2015-10-15 | — | — | WO | claimed |
| CN-115819346-B | Synthesis method of 3- (difluoromethyl) -1-methyl-1H-pyrazole-4-ethyl formate | 湖南化工研究院有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-221733297-U | Continuous production system of 1-methyl-3-difluoromethyl-1H-pyrazole-4-carboxylic acid | 天津凯莱英医药科技发展有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-114315577-B | Synthesis method of 2-ethoxymethylene-4, 4-difluoro acetoacetic acid ethyl ester | 湖南海利化工股份有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-114315577-B | Synthesis method of 2-ethoxymethylene-4, 4-difluoro acetoacetic acid ethyl ester | 湖南海利化工股份有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-117960075-A | Continuous production system and process of 1-methyl-3-difluoromethyl-1H-pyrazole-4-carboxylic acid | 天津凯莱英医药科技发展有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117720528-A | Oxadiazole sulfonamide compound containing pyrazole structure, and preparation method and application thereof | 贵州大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-117658919-A | Method for promoting efficient synthesis of 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid by alkaline ionic liquid | 江苏恒盛药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| EP-2496560-A1 | PROCESS FOR PREPARING 1,3-DISUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2012-09-12 | — | — | EP | disclosed |
| WO-2012025469-A1 | IMPROVED PROCESS FOR THE PREPARATION OF ESTERS OF 1-H-PYRAZOLE-4-CARBOXYLIC ACIDS | SOLVAY SA (BE) | 2012-03-01 | — | — | WO | disclosed |
| US-20110301181-A1 | halogen-substituted compounds | BAYER CROPSCIENCE AG (DE) | 2011-12-08 | — | — | US | disclosed |
| WO-2011054732-A1 | PROCESS FOR PREPARING 1,3-DISUBSTITUTED PYRAZOLE COMPOUNDS | BASF SE (DE) | 2011-05-12 | — | — | WO | disclosed |
| US-20100292236-A1 | 5-Membered Heterocyclic Amides And Related Compounds | H. LUNDBECK A/S (DK) | 2010-11-18 | — | — | US | disclosed |
| EP-2178865-A2 | 5-MEMBERED HETEROCYCLIC AMIDES AND RELATED COMPOUNDS | Lundbeck, H., A/S (DK) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009012482-A2 | 5-MEMBERED HETEROCYCLIC AMIDES AND RELATED COMPOUNDS | H.LUNDBECK A/S (DK) | 2009-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301181-A1 | halogen-substituted compounds | L3MBTL4, QSOX1, L3MBTL3 | EP300 3750/4885 |
| US-20100292236-A1 | 5-Membered Heterocyclic Amides And Related Compounds | GPR35, HCAR2, HCAR1 | EP300 876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.