Sugi Predict

Sugi Predict / Compounds / Benzamidoxime

Benzamidoxime

Benzamidoxime

SCHEMBL194059

N=C(NO)c1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC8 Q9BY41 3/20 0.50
▸ HDAC1 Q13547 3/20 0.50
▸ ALOX15 P16050 2/20 0.50
▸ IDO1 P14902 2/20 0.50
▸ HDAC3 O15379 1/20 0.50
▸ CA12 O43570 1/20 0.50
▸ CA1 P00915 1/20 0.50
▸ CA9 Q16790 1/20 0.50
▸ HDAC7 Q8WUI4 1/20 0.50
▸ HDAC2 Q92769 1/20 0.50
▸ HSD17B10 Q99714 1/20 0.50
▸ HDAC6 Q9UBN7 1/20 0.50
▸ NCOR2 Q9Y618 1/20 0.50
▸ F2 P00734 1/20 0.48
▸ F10 P00742 1/20 0.48
▸ F12 P00748 1/20 0.48
▸ F7 P08709 1/20 0.48
▸ F3 P13726 1/20 0.48
▸ PKM P14618 1/20 0.48
▸ BLM P54132 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20471083 0.87 TSHR (0.58) HDAC8HDAC1ALOX15IDO1HDAC3
SCHEMBL1009424 0.85 WDR5 (0.56) HDAC8HDAC1HDAC3HDAC7HDAC2
SCHEMBL12348299 0.85 HSD17B10 (0.36) HDAC8HDAC1ALOX15IDO1HDAC3
Benzamidoxime SCHEMBL30452573 0.82 HDAC8 (0.44) HDAC8HDAC1ALOX15IDO1HDAC3
SCHEMBL29788167 0.80 HDAC8 (0.61) HDAC8PRSS1PRSS2PRSS3
SCHEMBL16697738 0.80 MMP1 (0.51) HDAC8CA1F2F10PRSS1
SCHEMBL5067711 0.80 F2 (0.50) HDAC8HDAC1ALOX15IDO1HDAC3
SCHEMBL3198029 0.80 F2 (0.50) HDAC8HDAC1ALOX15IDO1HDAC3
SCHEMBL4403830 0.77 TSHR (0.57) ALOX15CA12CA1CA9CES1
SCHEMBL3557897 0.76 F2 (0.52) HDAC8HDAC1ALOX15IDO1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 886 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504727-A Synthesis method of 3-phenyl-5- (thiophene-2-yl) -1,2, 4-oxadiazole 石家庄市深泰化工有限公司 2025-02-25 — — CN claimed
CN-119371360-A 5, 6-Dihydroxypyrimidine compound and preparation method and application thereof 暨南大学 2025-01-28 — — CN claimed
US-12172972-B1 3-(3-bromophenyl)-5-((2-isopropyl-5-methylphenoxy)methyl)-1,2,4-oxadiazole as an anti-cancer and antimicrobial compound King Faisal University (SA) 2024-12-24 — — US claimed
US-12162845-B1 3-(4-bromophenyl)-5-((2-isopropyl-5-methylphenoxy)methyl)-1,2,4-oxadiazole as an anti-cancer and antimicrobial compound King Faisal University (SA) 2024-12-10 — — US claimed
CN-116355284-B DOPO-based reactive flame retardant for flame-retardant epoxy resin and preparation method thereof 福州大学 2024-06-07 — — CN claimed
US-11958816-B1 N′-({[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]acetyl}oxy)benzenecarboximidamide as an antimicrobial compound King Faisal University (SA) 2024-04-16 — — US claimed
US-11958814-B1 3-(4-nitrophenyl)-5-((2-isopropyl-5-methylphenoxy)methyl)-1,2,4-oxadiazole as an anti-cancer and antimicrobial compound King Faisal University (SA) 2024-04-16 — — US claimed
US-11919872-B1 N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)benzimidamide as an antimicrobial compound King Faisal University (SA) 2024-03-05 — — US claimed
US-11919871-B1 3-(3-chlorophenyl)-5-((2-isopropyl-5- methylphenoxy)methyl)-1,2,4-oxadiazole as an anti-cancer and antimicrobial compound King Faisal University (SA) 2024-03-05 — — US claimed
CN-112174853-B Method for preparing (Z) -N-hydroxy phenylamidine by ammonolysis 湖南经世新材料有限责任公司 2023-07-25 — — CN claimed
CN-108794460-A A kind of 1,2,4- oxadiazoles -3,4- dihydroquinoline type compounds and its preparation method and application 贵州医科大学 2018-11-13 — — CN claimed
CN-103951662-B Little molecule material of main part of a kind of 1,2,4-oxadiazole and preparation method thereof, application SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) 2016-05-04 — — CN claimed
CN-104860898-A 3-aryloxadiazole compound and use thereof UNIV SHENYANG PHARMACEUTICAL 2015-08-26 — — CN claimed
US-20120028955-A1 BICYCLIC MGLUR5 POSITIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING SAME VANDERBILT UNIVERSITY 2012-02-02 — — US claimed
US-20120028956-A1 BICYCLIC MGLUR5 POSITIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING SAME VANDERBILT UNIVERSITY 2012-02-02 — — US claimed
CN-102015651-A Compounds and compositions as TLR activity modulators IRM LLC 2011-04-13 — — CN claimed
US-20090270362-A1 BICYCLIC MGLUR5 POSITIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING SAME VANDERBILT UNIVERSITY 2009-10-29 — — US claimed
US-20090130849-A1 CHEMICAL MECHANICAL POLISHING AND WAFER CLEANING COMPOSITION COMPRISING AMIDOXIME COMPOUNDS AND ASSOCIATED METHOD FOR USE EKC TECHNOLOGY, INC. 2009-05-21 — — US claimed
WO-2009058274-A1 CHEMICAL MECHANICAL POLISHING AND WAFER CLEANING COMPOSITION COMPRISING AMIDOXIME COMPOUNDS AND ASSOCIATED METHOD FOR USE EKC TECHNOLOGY, INC. (US) 2009-05-07 — — WO claimed
US-20090111965-A1 NOVEL NITRILE AND AMIDOXIME COMPOUNDS AND METHODS OF PREPARATION EKC TECHNOLOGY, INC. 2009-04-30 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11958816-B1 N′-({[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]acetyl}oxy)benzenecarboximidamide as an antimicrobial compound AADAC, B3GNT2, OGA HDAC8 57/4885HDAC1 33/4885ALOX15 1044/4885
US-20120028955-A1 BICYCLIC MGLUR5 POSITIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING SAME GRM5, GRIK5, GRM1 HDAC8 1475/4885HDAC1 1090/4885ALOX15 3410/4885
US-11919871-B1 3-(3-chlorophenyl)-5-((2-isopropyl-5- methylphenoxy)methyl)-1,2,4-oxadiazole as an anti-cancer and antimicrobial compound OXA1L, API5, CASP3 HDAC8 1086/4885HDAC1 277/4885ALOX15 2618/4885
US-20120028956-A1 BICYCLIC MGLUR5 POSITIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING SAME GRM5, GRIK5, GRM1 HDAC8 1475/4885HDAC1 1090/4885ALOX15 3410/4885
US-12172972-B1 3-(3-bromophenyl)-5-((2-isopropyl-5-methylphenoxy)methyl)-1,2,4-oxadiazole as an anti-cancer and antimicrobial compound OXA1L, API5, CASP3 HDAC8 806/4885HDAC1 145/4885ALOX15 2758/4885
US-12162845-B1 3-(4-bromophenyl)-5-((2-isopropyl-5-methylphenoxy)methyl)-1,2,4-oxadiazole as an anti-cancer and antimicrobial compound OXA1L, API5, CASP3 HDAC8 697/4885HDAC1 135/4885ALOX15 2729/4885
US-11919872-B1 N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)benzimidamide as an antimicrobial compound NIT2, B3GNT2, NAAA HDAC8 566/4885HDAC1 413/4885ALOX15 2582/4885
US-11958814-B1 3-(4-nitrophenyl)-5-((2-isopropyl-5-methylphenoxy)methyl)-1,2,4-oxadiazole as an anti-cancer and antimicrobial compound OXA1L, API5, CASP3 HDAC8 526/4885HDAC1 189/4885ALOX15 2363/4885
US-20090111965-A1 NOVEL NITRILE AND AMIDOXIME COMPOUNDS AND METHODS OF PREPARATION GNMT, NIT2, NNMT HDAC8 3327/4885HDAC1 4108/4885ALOX15 669/4885
US-20090270362-A1 BICYCLIC MGLUR5 POSITIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING SAME GRM5, GRIK5, GRM1 HDAC8 1475/4885HDAC1 1090/4885ALOX15 3410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.