SCHEMBL1940876

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17051119	0.85	BRD4 (0.43)	BRD4ATRBRD9NPC1RAB9A
	SCHEMBL4035121	0.83	BRD4 (0.39)	BRD4ATRALDH1A1BRD9NPC1
	SCHEMBL1942386	0.82	HTR6 (0.40)	ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
	SCHEMBL1943580	0.79	BRD4 (0.36)	BRD4ATRALDH1A1CYP1A2CYP3A4
	SCHEMBL1941286	0.79	BRD4 (0.36)	BRD4ATRBRD9NPC1RAB9A
	SCHEMBL12659342	0.76	HTR6 (0.38)	ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
	SCHEMBL1941351	0.75	LCK (0.35)	BRD4ATRBRD9NPC1RAB9A
	SCHEMBL21436566	0.72	EPHB3 (0.54)	ALDH1A1BRD9NPC1RAB9AMEN1
	SCHEMBL31324819	0.71	EGFR (0.46)	BRD4ALDH1A1CYP1A2CYP3A4CYP2D6
	SCHEMBL7826478	0.69	MEN1 (0.36)	ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.