SCHEMBL194615

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL194510	0.83	ALDH1A1 (0.51)	ALDH1A1GAAHPGDGLAMEN1
	SCHEMBL194441	0.82	ATM (0.50)	ALDH1A1GAAHPGDGLAATM
	SCHEMBL194333	0.82	KDM4E (0.51)	ALDH1A1GAAHPGDGLAMEN1
	SCHEMBL28522608	0.81	MAOA (0.51)	ALDH1A1GAAHPGDGLAATM
	SCHEMBL28332090	0.76	KMT2A (0.55)	ALDH1A1GAAHPGDGLAATM
	SCHEMBL193547	0.76	AR (0.44)	ALDH1A1GAAHPGDKDM4EBLM
	SCHEMBL28510561	0.74	MAOA (0.52)	ALDH1A1GAAHPGDGLAATM
	SCHEMBL194064	0.74	KDM4E (0.41)	ALDH1A1GAAHPGDGLAATM
	SCHEMBL13182042	0.73	PTGES (0.43)	ALDH1A1GAAMEN1KMT2AMAPT
	SCHEMBL194128	0.73	AXL (0.45)	ALDH1A1GAAKMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.