Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 16/20 | 0.47 |
| ▸ | ABL1 | P00519 | 13/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 11/20 | 0.47 |
| ▸ | EGFR | P00533 | 11/20 | 0.47 |
| ▸ | HCK | P08631 | 11/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 11/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 11/20 | 0.47 |
| ▸ | MTOR | P42345 | 11/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 11/20 | 0.47 |
| ▸ | EPHB4 | P54760 | 11/20 | 0.47 |
| ▸ | PRKDC | P78527 | 11/20 | 0.47 |
| ▸ | KDR | P35968 | 10/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 10/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214 | 0.90 | DYRK1A (0.48) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL149180 | 0.88 | PIK3CD (0.55) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL20093481 | 0.87 | KMO (0.46) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL11306 | 0.85 | SRC (0.47) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL17626717 | 0.83 | PIK3CD (0.47) | PIK3CDEGFRPIK3CAPIK3CBPIK3CG | |
| SCHEMBL16665685 | 0.83 | PIK3CD (0.67) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL10811 | 0.82 | SRC (0.57) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL20093445 | 0.82 | EGFR (0.50) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL13293328 | 0.81 | ERBB2 (0.56) | EGFR | |
| SCHEMBL17365228 | 0.81 | PDGFRB (0.46) | SRCABL1PIK3CDEGFRHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858907-B2 | Kinase modulators | RHIZEN PHARMACEUTICALS AG (CH) | 2024-01-02 | — | — | US | disclosed |
| US-11020399-B2 | Intermediates useful in the synthesis of compounds as modulators of protein kinases | RHIZEN PHARMACEUTICALS SA (CH) | 2021-06-01 | — | — | US | disclosed |
| US-20190282581-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | RHIZEN PHARMACEUTICALS AG (CH) | 2019-09-19 | — | — | US | disclosed |
| US-9775841-B2 | Compounds as modulators of protein kinases | RHIZEN PHARMACEUTICALS SA (CH) | 2017-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11020399-B2 | Intermediates useful in the synthesis of compounds as modulators of protein kinases | MAP4K2, MAP3K20, MAP3K1 | SRC 85/4885ABL1 106/4885PIK3CD 288/4885 |
| US-20190282581-A1 | NOVEL COMPOUNDS AS MODULATORS OF PROTEIN KINASES | PRKCA, PRKCH, PRKCB | SRC 285/4885ABL1 334/4885PIK3CD 47/4885 |
| US-11858907-B2 | Kinase modulators | RPS6KA1, RPS6KA2, PRKAR2A | SRC 110/4885ABL1 258/4885PIK3CD 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.