Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15317942 | 0.83 | LMNA (0.46) | SUV39H2LMNASMN1; SMN2HSD17B10MEN1 | |
| SCHEMBL19445764 | 0.79 | KLKB1 (0.40) | TSHR | |
| SCHEMBL19445644 | 0.79 | ERAP2 (0.44) | SUV39H2AAK1LTA4HTERT | |
| SCHEMBL19445719 | 0.75 | KLKB1 (0.41) | LMNAHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL12885646 | 0.73 | ALDH1A1 (0.57) | LMNASMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL17737202 | 0.72 | HSD17B10 (0.52) | SMN1; SMN2HSD17B10MEN1MAPTKMT2A | |
| SCHEMBL23729020 | 0.71 | LTA4H (0.49) | LMNASMN1; SMN2HSD17B10MEN1MAPT | |
| SCHEMBL13815084 | 0.71 | SUV39H2 (0.51) | SUV39H2LMNAMEN1KMT2AAAK1 | |
| SCHEMBL13319568 | 0.71 | SUV39H2 (0.51) | SUV39H2AAK1LTA4HTERT | |
| SCHEMBL20215616 | 0.71 | SUV39H2 (0.49) | SUV39H2AAK1LTA4HTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |