Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | EPOR | P19235 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25689671 | 0.79 | HSD17B10 (0.48) | HSD17B10CA1CA2CA7CA14 | |
| SCHEMBL21726052 | 0.76 | CA1 (0.51) | LTA4HCA1CA2KMT2AKLKB1 | |
| SCHEMBL24774255 | 0.75 | LTA4H (0.49) | LTA4HCA1CA2EPORHDAC2 | |
| SCHEMBL22299573 | 0.75 | HSD17B10 (0.44) | LTA4HHSD17B10CA1CA2CA7 | |
| SCHEMBL25148090 | 0.75 | HSD17B10 (0.44) | LTA4HHSD17B10CA1CA2CA7 | |
| SCHEMBL21263588 | 0.73 | LTA4H (0.50) | LTA4HCA1CA2HDAC2KLKB1 | |
| SCHEMBL21205411 | 0.73 | HSD17B10 (0.43) | HSD17B10CA1CA2CA7CA14 | |
| SCHEMBL21875528 | 0.73 | HSD17B10 (0.46) | HSD17B10CA1CA2CA7CA14 | |
| SCHEMBL17737202 | 0.73 | HSD17B10 (0.52) | HSD17B10MEN1KMT2AMAPTNPC1 | |
| SCHEMBL16418621 | 0.72 | KLKB1 (0.49) | LTA4HCA1CA2HDAC2KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11077201-B2 | Immunoconjugates with an intracellularly-cleavable linkage | IMMUNOMEDICS, INC. (US) | 2021-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11077201-B2 | Immunoconjugates with an intracellularly-cleavable linkage | CD47, CD44, DNPEP | LTA4H 2078/4885HSD17B10 2826/4885CA1 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.