SCHEMBL194623

SCHEMBL194623

COc1ccc(C(=N)NO)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.59
CA2 P00918 6/20 0.59
PRSS1 P07477 1/20 0.57
PRSS2 P07478 1/20 0.57
PRSS3 P35030 1/20 0.57
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
MMP1 P03956 1/20 0.49
PLK1 P53350 1/20 0.48
CA12 O43570 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
PTGIR P43119 1/20 0.47
MEN1 O00255 1/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
MAPK1 P28482 1/20 0.47
RAB9A P51151 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18795927 0.89 PTGIR (0.65) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL1545285 0.83 PLK1 (0.59) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL2646271 0.81 PRSS1 (0.61) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL12348299 0.81 HSD17B10 (0.36) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL9874228 0.79 NPC1 (0.61) PRSS1PRSS2PRSS3MEN1LMNA
SCHEMBL12332579 0.79 PRSS1 (0.53) CA1CA2PRSS1PRSS2PRSS3
Iodide SCHEMBL10985397 0.79 PRSS1 (0.59) CA1CA2PRSS1PRSS2PRSS3
Hydrochloric Acid SCHEMBL4397004 0.79 PRSS1 (0.59) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL2698404 0.78 ALDH1A1 (0.48) CA1CA2PRSS1PRSS2PRSS3
SCHEMBL17055827 0.78 KMT2A (0.53) MEN1LMNAMAPTMAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12180172-B1 [3-(4-Methoxyphenyl)-1,2,4-oxadiazol-5-yl]methanol as an antitumor and antimicrobial compound King Faisal University (SA) 2024-12-31 US claimed
US-11981647-B1 3-(4-methoxyphenyl)-5-{[5-methyl-2-(propan-2-yl)phenoxy]methyl}-1,2,4-oxadiazole as an antitumor and antimicrobial compound King Faisal University (SA) 2024-05-14 US claimed
US-11897850-B1 N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)-4-methoxybenzimidamide as an antimicrobial compound King Faisal University (SA) 2024-02-13 US claimed
US-11891366-B1 4-methoxy-n′-(2-(5-phenyl-1,3,4-oxadiazol-2-ylthio)acetoxy)benzimidamide as an antimicrobial compound King Faisal University (SA) 2024-02-06 US claimed
US-12478621-B2 Substituted aminoquinolones as dgkalpha inhibitors for immune activation DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2025-11-25 US disclosed
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 US disclosed
US-12275723-B2 Compounds and uses thereof JANSSEN PHARMACEUTICA NV (BE) 2025-04-15 US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 US disclosed
US-20250091999-A1 [3-(4-METHOXYPHENYL)-1,2,4-OXADIAZOL-5-YL]METHANOL AS AN ANTITUMOR AND ANTIMICROBIAL COMPOUND UNIV KING FAISAL (SA) 2025-03-20 US disclosed
US-12180172-B1 [3-(4-Methoxyphenyl)-1,2,4-oxadiazol-5-yl]methanol as an antitumor and antimicrobial compound King Faisal University (SA) 2024-12-31 US disclosed
US-20240400546-A1 COMPOUNDS AND USES THEREOF JANSSEN PHARMACEUTICA NV (BE) 2024-12-05 US disclosed
WO-2005044797-A1 ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS ADDEX PHARMACEUTICALS SA (CH) 2005-05-19 WO disclosed
EP-1373264-B1 3-HETEROCYCLYLPROPANOHYDROXAMIC ACID AS PROCOLLAGEN C-PROTEINASE INHIBITORS PFIZER LTD (GB) 2004-12-22 EP disclosed
US-6821972-B2 ANTISCARRING AGENTS; WOUND HEALING AGENTS; ENZYME INHIBITORS PFIZER INC. 2004-11-23 US disclosed
EP-1423120-A1 2H-PHTHALAZIN-1-ONES AND METHODS FOR USE THEREOF ICOS CORPORATION (US) 2004-06-02 EP disclosed
US-20040087588-A1 Parp inhibitors ICOS CORPORATION 2004-05-06 US disclosed
WO-2004037248-A2 MODULATION OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS ACTIVITY CAREX SA (FR) 2004-05-06 WO disclosed
US-20030069291-A1 3-heterocyclylpropanohydroxamic acid PCP inhibitors PFIZER INC. 2003-04-10 US disclosed
WO-2003015785-A1 2H-PHTHALAZIN-1-ONES AND METHODS FOR USE THEREOF ICOS CORPORATION (US) 2003-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11891366-B1 4-methoxy-n′-(2-(5-phenyl-1,3,4-oxadiazol-2-ylthio)acetoxy)benzimidamide as an antimicrobial compound IL4I1, AADAC, CASP4 CA1 4830/4885CA2 3688/4885PRSS1 3392/4885
US-20040087588-A1 Parp inhibitors PARP1, PARP2, PARP11 CA1 3375/4885CA2 1869/4885PRSS1 748/4885
US-20250091999-A1 [3-(4-METHOXYPHENYL)-1,2,4-OXADIAZOL-5-YL]METHANOL AS AN ANTITUMOR AND ANTIMICROBIAL COMPOUND OXA1L, MCL1, CASP3 CA1 4569/4885CA2 4344/4885PRSS1 4312/4885
US-20240400546-A1 COMPOUNDS AND USES THEREOF NLN, ACHE, CLN6 CA1 354/4885CA2 880/4885PRSS1 1923/4885
US-12478621-B2 Substituted aminoquinolones as dgkalpha inhibitors for immune activation DGKK, DGKG, DGKA CA1 4797/4885CA2 4385/4885PRSS1 3296/4885
US-12275723-B2 Compounds and uses thereof NLN, ACHE, CLN6 CA1 354/4885CA2 880/4885PRSS1 1923/4885
US-11897850-B1 N′-(2-(5-(4-chlorophenyl)-1,3,4-oxadiazol-2-ylthio)acetoxy)-4-methoxybenzimidamide as an antimicrobial compound B3GNT2, IL4I1, NIT2 CA1 4834/4885CA2 3369/4885PRSS1 4137/4885
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 CA1 4646/4885CA2 4503/4885PRSS1 3626/4885
US-12180172-B1 [3-(4-Methoxyphenyl)-1,2,4-oxadiazol-5-yl]methanol as an antitumor and antimicrobial compound OXA1L, MCL1, CASP3 CA1 4569/4885CA2 4344/4885PRSS1 4312/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 CA1 4646/4885CA2 4503/4885PRSS1 3626/4885
US-11981647-B1 3-(4-methoxyphenyl)-5-{[5-methyl-2-(propan-2-yl)phenoxy]methyl}-1,2,4-oxadiazole as an antitumor and antimicrobial compound OXA1L, API5, MCL1 CA1 4848/4885CA2 4647/4885PRSS1 4534/4885
US-20030069291-A1 3-heterocyclylpropanohydroxamic acid PCP inhibitors PAH, CYP2F1, CYP7A1 CA1 1396/4885CA2 1578/4885PRSS1 1745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.