Water

Water

SCHEMBL1946236

O.O.O.O.O.O.O.O.O.O.OOB(O)O.[NaH]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL10896513 1.00
Water SCHEMBL8587972 1.00
Water SCHEMBL21333 1.00
Water SCHEMBL78471 1.00
Water SCHEMBL37908 1.00
Water SCHEMBL80313 1.00
SCHEMBL1408311 0.95
Water SCHEMBL6226530 0.95 LMNA (0.30)
Water SCHEMBL3651763 0.95 LMNA (0.30)
Water SCHEMBL61018 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008077108-A1 OPHTHALMIC AND CONTACT LENS SOLUTIONS WITH A PEROXIDE SOURCE AND A PRESERVATIVE FXS VENTURES, LLC (US) 2008-06-26 WO claimed
US-20070098813-A1 OPHTHALMIC AND CONTACT LENS SOLUTIONS WITH A PEROXIDE SOURCE AND A PRESERVATIVE FXS VENTURES, LLC 2007-05-03 US claimed
US-20060078626-A1 Opthalmic and contact lens solutions with a peroxide source and a cationic polymeric preservative BIOCONCEPT LABORATORIES 2006-04-13 US claimed
EP-1337262-A4 IMPROVED OPHTHALMIC AND CONTACT LENS SOLUTIONS WITH A PEROXIDE SOURCE AND A CATIONIC POLYMERIC PRESERVATIVE BIO CONCEPT LAB (US) 2006-02-08 EP claimed
EP-1337262-A2 IMPROVED OPHTHALMIC AND CONTACT LENS SOLUTIONS WITH A PEROXIDE SOURCE AND A CATIONIC POLYMERIC PRESERVATIVE Bio-Concept Laboratories (US) 2003-08-27 EP claimed
WO-2002040062-A2 IMPROVED OPHTHALMIC AND CONTACT LENS SOLUTIONS WITH A PEROXIDE SOURCE AND A CATIONIC POLYMERIC PRESERVATIVE BIO-CONCEPT LABORATORIES (US) 2002-05-23 WO claimed
US-5807585-A FOR CONTACT LENSES; CONTAINING HYDROGEN PEROXIDE CIBA VISION CORPORATION (US) 1998-09-15 US claimed
EP-0354186-B1 A method of preserving ophthalmic solutions and compositions therefor CIBA GEIGY AG (CH) 1996-08-28 EP claimed
EP-0706802-A2 A method of preserving ophthalmic solutions and compositions therefor CIBA-GEIGY AG (CH) 1996-04-17 EP claimed
EP-0354186-A1 A method of preserving ophthalmic solutions and compositions therefor CIBA-GEIGY AG (CH) 1990-02-07 EP claimed
CN-115448341-B Preparation method of flaky beta alumina 广西大学 2024-06-11 CN disclosed
US-20200289699-A1 L-HISTIDINE AND VITAMIN B IN OPHTHALMIC SOLUTIONS FXS VENTURES, LLC 2020-09-17 US disclosed
US-20200069576-A1 COMPOSITIONS CONTAINING ALPHA-2-ADRENERGIC AGONIST COMPONENTS ALLERGAN INC (US) 2020-03-05 US disclosed
US-10307368-B2 Compositions containing alpha-2-adrenergic agonist components ALLERGAN, INC. (US) 2019-06-04 US disclosed
US-20180021254-A1 COMPOSITIONS CONTAINING ALPHA-2-ADRENERGIC AGONIST COMPONENTS ALLERGAN INC (US) 2018-01-25 US disclosed
EP-0354186-B1 A method of preserving ophthalmic solutions and compositions therefor CIBA GEIGY AG (CH) 1996-08-28 EP disclosed
EP-0706802-A2 A method of preserving ophthalmic solutions and compositions therefor CIBA-GEIGY AG (CH) 1996-04-17 EP disclosed
EP-0698081-A1 PROCESS FOR CONSOLIDATING PARTICULATE SOLIDS AND CLEANING PRODUCTS THEREFROM Henkel-Ecolab GmbH & Co. OHG (DE) 1996-02-28 EP disclosed
WO-1994025563-A1 PROCESS FOR CONSOLIDATING PARTICULATE SOLIDS AND CLEANING PRODUCTS THEREFROM HENKEL-ECOLAB GMBH & CO. OHG (DE) 1994-11-10 WO disclosed
EP-0354186-A1 A method of preserving ophthalmic solutions and compositions therefor CIBA-GEIGY AG (CH) 1990-02-07 EP disclosed