SCHEMBL19463178

SCHEMBL19463178

COc1c(C)c(CCCO)c(C)c(OC)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS2 Q9H2K2 1/20 0.42
IMPDH2 P12268 4/20 0.40
IMPDH1 P20839 4/20 0.40
ALOX5 P09917 6/20 0.37
KDM4E B2RXH2 2/20 0.34
LMNA P02545 1/20 0.33
PGR P06401 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
MAOA P21397 1/20 0.33
TBXA2R P21731 1/20 0.33
MAPK1 P28482 1/20 0.33
AVPR2 P30518 1/20 0.33
CYP2C19 P33261 1/20 0.33
HTR2B P41595 1/20 0.33
HTT P42858 1/20 0.33
PDE3A Q14432 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8293476 0.82 TNKS2 (0.41) TNKS2IMPDH2IMPDH1ALOX5KDM4E
SCHEMBL8564172 0.81 IMPDH2 (0.41) TNKS2IMPDH2IMPDH1ALOX5KDM4E
SCHEMBL1242706 0.81 TNKS2 (0.35) TNKS2IMPDH2IMPDH1ALOX5KDM4E
SCHEMBL19463880 0.81 ALOX5 (0.41) IMPDH2IMPDH1ALOX5PDE3A
SCHEMBL22172495 0.78 LMNA (0.42) IMPDH2IMPDH1ALOX5LMNAPGR
SCHEMBL7323576 0.76 ALOX5 (0.38) TNKS2IMPDH2IMPDH1ALOX5LMNA
SCHEMBL19463497 0.76 IMPDH2 (0.37) IMPDH2IMPDH1ALOX5TDP1CA2
SCHEMBL1784681 0.75 IMPDH1 (0.40) TNKS2IMPDH2IMPDH1ALOX5LMNA
SCHEMBL11098325 0.75 LMNA (0.40) TNKS2IMPDH2IMPDH1ALOX5LMNA
SCHEMBL1241214 0.75 ALOX5 (0.41) TNKS2IMPDH2IMPDH1ALOX5LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3442938-B1 PRODUCTION OF MONOMERS FROM LIGNIN DURING DEPOLYMERISATION OF LIGNOCELLULOSE-CONTAINING COMPOSITION ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2025-11-19 EP disclosed
US-11639324-B2 Production of monomers from lignin during depolymerization of lignocellulose-containing composition ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2023-05-02 US disclosed
US-11639324-B2 Production of monomers from lignin during depolymerization of lignocellulose-containing composition ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2023-05-02 US disclosed
CN-109328185-B Preparation of monomers derived from lignin during depolymerization of lignocellulose-containing compositions 洛桑联邦理工大学 2022-04-12 CN disclosed
US-20210107851-A1 Production of Monomers from Lignin During Depolymerization of Lignocellulose-Containing Composition ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2021-04-15 US disclosed
US-20210107851-A1 Production of Monomers from Lignin During Depolymerization of Lignocellulose-Containing Composition ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2021-04-15 US disclosed
US-10906856-B2 Production of monomers from lignin during depolymerization of lignocellulose-containing composition ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2021-02-02 US disclosed
US-10906856-B2 Production of monomers from lignin during depolymerization of lignocellulose-containing composition ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2021-02-02 US disclosed
US-20190127304-A1 Production of Monomers from Lignin During Depolymerization of Lignocellulose-Containing Composition ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2019-05-02 US disclosed
US-20190127304-A1 Production of Monomers from Lignin During Depolymerization of Lignocellulose-Containing Composition ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2019-05-02 US disclosed
EP-3442938-A1 PRODUCTION OF MONOMERS FROM LIGNIN DURING DEPOLYMERISATION OF LIGNOCELLULOSE-CONTAINING COMPOSITION Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) 2019-02-20 EP disclosed
CN-109328185-A Preparation of monomers derived from lignin during depolymerization of lignocellulose-containing compositions 洛桑联邦理工大学 2019-02-12 CN disclosed
WO-2017178513-A1 PRODUCTION OF MONOMERS FROM LIGNIN DURING DEPOLYMERISATION OF LIGNOCELLULOSE-CONTAINING COMPOSITION ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2017-10-19 WO disclosed
WO-2017178513-A1 PRODUCTION OF MONOMERS FROM LIGNIN DURING DEPOLYMERISATION OF LIGNOCELLULOSE-CONTAINING COMPOSITION ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2017-10-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10906856-B2 Production of monomers from lignin during depolymerization of lignocellulose-containing composition DCXR, LCT, MLEC TNKS2 1862/4885IMPDH2 1447/4885IMPDH1 1462/4885
US-11639324-B2 Production of monomers from lignin during depolymerization of lignocellulose-containing composition DCXR, LCT, MLEC TNKS2 1862/4885IMPDH2 1447/4885IMPDH1 1462/4885
US-20190127304-A1 Production of Monomers from Lignin During Depolymerization of Lignocellulose-Containing Composition DCXR, LCT, MLEC TNKS2 1862/4885IMPDH2 1447/4885IMPDH1 1462/4885
US-20210107851-A1 Production of Monomers from Lignin During Depolymerization of Lignocellulose-Containing Composition DCXR, LCT, MLEC TNKS2 1862/4885IMPDH2 1447/4885IMPDH1 1462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.