Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | CTSC | P53634 | 2/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18506593 | 0.86 | CTSC (0.56) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL20669159 | 0.84 | MMP1 (0.61) | CTSC | |
| SCHEMBL12202126 | 0.84 | CTSC (0.60) | CTSCOPRD1OPRM1OPRK1SLC15A1 | |
| SCHEMBL7410429 | 0.84 | HDAC3 (0.65) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7410433 | 0.84 | HDAC3 (0.65) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7694204 | 0.84 | SLC15A1 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL19465132 | 0.84 | SLC15A1 (0.60) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL1329567 | 0.82 | MME (0.67) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL5065345 | 0.82 | MME (0.67) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL825577 | 0.82 | MME (0.67) | CTSCALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11021706-B2 | Antisense antibacterial compounds and methods | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-06-01 | — | — | US | disclosed |
| US-10907158-B2 | Antisense antibacterial compounds and methods | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-02-02 | — | — | US | disclosed |
| US-20200032254-A1 | ANTISENSE ANTIBACTERIAL COMPOUNDS AND METHODS | OREGON STATE UNIVERSITY | 2020-01-30 | — | — | US | disclosed |
| US-10391098-B2 | Antisense antibacterial compounds and methods | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-08-27 | — | — | US | disclosed |
| US-20190078095-A1 | ANTISENSE ANTIBACTERIAL COMPOUNDS AND METHODS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-03-14 | — | — | US | disclosed |
| US-9790495-B2 | Antisense antibacterial compounds and methods | OREGON STATE UNIVERSITY (US) | 2017-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190078095-A1 | ANTISENSE ANTIBACTERIAL COMPOUNDS AND METHODS | FBL, RNGTT, ZFR | HDAC3 1992/4885HDAC4 1701/4885HDAC1 1911/4885 |
| US-10907158-B2 | Antisense antibacterial compounds and methods | FBL, RNGTT, ZFR | HDAC3 1992/4885HDAC4 1701/4885HDAC1 1911/4885 |
| US-11021706-B2 | Antisense antibacterial compounds and methods | RNGTT, ZFR, UPF1 | HDAC3 1660/4885HDAC4 1433/4885HDAC1 2144/4885 |
| US-10391098-B2 | Antisense antibacterial compounds and methods | RNGTT, POLRMT, POLM | HDAC3 2369/4885HDAC4 1256/4885HDAC1 1810/4885 |
| US-20200032254-A1 | ANTISENSE ANTIBACTERIAL COMPOUNDS AND METHODS | RNGTT, ZFR, UPF1 | HDAC3 1660/4885HDAC4 1433/4885HDAC1 2144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.