Sugi Predict

Sugi Predict / Compounds / SCHEMBL1948571

SCHEMBL1948571

SCHEMBL1948571

N#Cc1cccc(-c2c(I)[c]c(C(F)(F)F)cc2C(F)(C(F)(F)F)C(F)(F)F)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAT2A P31153 1/20 0.36
▸ PTPN5 P54829 1/20 0.36
▸ TGFBR1 P36897 1/20 0.35
▸ ENPP1 P22413 1/20 0.35
▸ CLK4 Q9HAZ1 1/20 0.35
▸ PDK2 Q15119 2/20 0.34
▸ SYK P43405 2/20 0.34
▸ PTGDR2 Q9Y5Y4 1/20 0.34
▸ AR P10275 3/20 0.33
▸ FNTA P49354 1/20 0.33
▸ FNTB P49356 1/20 0.33
▸ CNR2 P34972 1/20 0.33
▸ RORC P51449 1/20 0.33
▸ TRPA1 O75762 1/20 0.33
▸ PGR P06401 1/20 0.33
▸ ADORA2A P29274 1/20 0.33
▸ ADORA2B P29275 1/20 0.33
▸ ADORA1 P30542 1/20 0.33
▸ PDK1 Q15118 1/20 0.33
▸ PDK3 Q15120 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1947965 0.94 MAT2A (0.34) MAT2APTPN5TGFBR1ENPP1CLK4
SCHEMBL1949835 0.88 PTPN5 (0.37) MAT2APTPN5TGFBR1ENPP1CLK4
SCHEMBL1949350 0.86 PTPN5 (0.36) MAT2APTPN5TGFBR1ENPP1CLK4
SCHEMBL1948959 0.86 KIF11 (0.40) PTPN5ARTRPA1
SCHEMBL1948131 0.85 ENPP1 (0.39) MAT2APTPN5TGFBR1ENPP1CLK4
SCHEMBL1951047 0.82 CYP11B2 (0.35) MAT2ATGFBR1
SCHEMBL1947933 0.82 PTPN5 (0.35) MAT2APTPN5TGFBR1ENPP1CLK4
SCHEMBL1950235 0.81 KIF11 (0.38) —
SCHEMBL1951318 0.80 ENPP1 (0.38) MAT2APTPN5TGFBR1ENPP1CLK4
SCHEMBL1948399 0.78 KIF11 (0.37) PTPN5TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9084420-B2 Amide derivative, pest control agent containing the amide derivative, and pest controlling method MITSUI CHEMICALS AGRO, INC. (JP) 2015-07-21 — — US disclosed
US-20140107368-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD MITSUI CHEMICALS AGRO, INC. (JP) 2014-04-17 — — US disclosed
US-8633228-B2 Amide derivative, pest control agent containing the amide derivative, and pest controlling method MITSUI CHEMICALS AGRO, INC. (JP) 2014-01-21 — — US disclosed
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD Mitsui Chemicals Agro., Inc. (JP) 2011-06-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110136878-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD L3MBTL1, L3MBTL4, L3MBTL3 MAT2A 3020/4885PTPN5 1167/4885TGFBR1 1620/4885
US-20140107368-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND PEST CONTROLLING METHOD L3MBTL1, L3MBTL4, L3MBTL3 MAT2A 3020/4885PTPN5 1167/4885TGFBR1 1620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.