SCHEMBL19487308

SCHEMBL19487308

CCN(C)C(C)(C)CNC(=O)c1cc(CI)on1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 11/20 0.43
HPGD P15428 1/20 0.43
SMN1; SMN2 Q16637 9/20 0.41
POLB P06746 1/20 0.41
THRB P10828 1/20 0.41
NPC1 O15118 9/20 0.40
ALDH1A1 P00352 2/20 0.38
MAPK1 P28482 1/20 0.36
SLC6A5 Q9Y345 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19483631 0.91 THRB (0.50) RAB9AHPGDSMN1; SMN2POLBTHRB
SCHEMBL19487504 0.88 RAB9A (0.44) RAB9AHPGDSMN1; SMN2POLBTHRB
SCHEMBL19487694 0.86 RAB9A (0.42) RAB9AHPGDSMN1; SMN2POLBTHRB
SCHEMBL19487693 0.82 RAB9A (0.43) RAB9AHPGDSMN1; SMN2POLBTHRB
SCHEMBL19484164 0.81 SLC6A5 (0.41) RAB9AHPGDSMN1; SMN2THRBNPC1
SCHEMBL19483622 0.81 THRB (0.48) RAB9AHPGDSMN1; SMN2POLBTHRB
SCHEMBL19483625 0.80 THRB (0.52) RAB9AHPGDSMN1; SMN2POLBTHRB
SCHEMBL19488049 0.80 RAB9A (0.42) RAB9AHPGDSMN1; SMN2POLBTHRB
SCHEMBL19483610 0.79 THRB (0.46) RAB9AHPGDSMN1; SMN2POLBTHRB
SCHEMBL19483658 0.79 THRB (0.51) RAB9AHPGDSMN1; SMN2POLBTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10251396-B2 Amide compound and use of same for noxious arthropod control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-04-09 US disclosed
US-20170295789-A1 AMIDE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170295789-A1 AMIDE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL OPRM1, TRPA1, L3MBTL3 RAB9A 753/4885HPGD 2430/4885SMN1; SMN2 1274/4885
US-10251396-B2 Amide compound and use of same for noxious arthropod control OPRM1, TRPA1, L3MBTL3 RAB9A 753/4885HPGD 2430/4885SMN1; SMN2 1274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.